Journal ArticleDOI
Encoded evidence: DNA in forensic analysis
Mark A. Jobling,Peter Gill +1 more
TLDR
For example, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases as mentioned in this paper.Abstract:
Sherlock Holmes said "it has long been an axiom of mine that the little things are infinitely the most important", but never imagined that such a little thing, the DNA molecule, could become perhaps the most powerful single tool in the multifaceted fight against crime. Twenty years after the development of DNA fingerprinting, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases.read more
Citations
More filters
Posted ContentDOI
Rare variant enriched identity-by-descent enables the detection of distant relatedness and older divergence between populations
TL;DR: A metric that leverages rare-variants shared between individuals to improve the detection of short IBD segments and can benefit association analyses, IBD mapping analyses, and demographic inferences is described.
La Genética forense y sus aplicaciones
TL;DR: The genetica forense, e.g. as discussed by the authors, is un adjetivo that indicates referencia a temas judiciales, i.e., the use of the field of forensic science for resolver crimes.
Genetic Diversity in Totonacan-Speaking Populations from Veracruz and Puebla States of Mexico
TL;DR: The analysis of genetic diversity in the Totonac will further enable the reconstruction of prehistoric events and maternal patterns of migration within Central Mexico and suggest limited maternal admixture with non-native populations introduced to Mexico as slaves in the last 500 years.
Proceedings ArticleDOI
An integrated DNA decision support system using grid environment for crime investigation
TL;DR: In this paper, a new architecture of integrated system in handling DNA profile match for identifying possible criminal and convicted offenders is proposed, and a new visual forensic DNA analysis tool is developed to help criminal investigators to analyze DNA data and DNA profile.
Book ChapterDOI
Skeletal microstructure, bone diagenesis, optimal sample selection, and pre-processing preparation techniques for DNA testing
TL;DR: In this article , a number of steps that can be taken in the laboratory to maximize DNA recovery and promote success of downstream genetic testing efforts are discussed. But, these steps are largely dependent on specific environmental conditions and the expertise of the laboratory scientist processing the remains.
References
More filters
Journal ArticleDOI
Hypervariable 'minisatellite' regions in human DNA.
TL;DR: A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA ‘fingerprint’ of general use in human genetic analysis.
Book ChapterDOI
The Apportionment of Human Diversity
TL;DR: Lewontin this article pointed out that even in the present era of Darwinism there is considerable diversity of opinion about the amount or importance of intragroup variation as opposed to the variation between races and species.
Journal ArticleDOI
Individual-specific 'fingerprints' of human DNA.
TL;DR: It is shown that other variant (core)n probes can detect additional sets of hypervariable minisatellites to produce somatically stable DNA ‘fingerprints’ which are completely specific to an individual (or to his or her identical twin) and can be applied directly to problems of human identification, including parenthood testing.