Journal ArticleDOI
Encoded evidence: DNA in forensic analysis
Mark A. Jobling,Peter Gill +1 more
TLDR
For example, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases as mentioned in this paper.Abstract:
Sherlock Holmes said "it has long been an axiom of mine that the little things are infinitely the most important", but never imagined that such a little thing, the DNA molecule, could become perhaps the most powerful single tool in the multifaceted fight against crime. Twenty years after the development of DNA fingerprinting, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases.read more
Citations
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Journal ArticleDOI
GenoPri'17: International Workshop on Genome Privacy and Security
TL;DR: The four papers in this special section were presented at the 4th International Workshop on Genome Privacy and Security GenoPri in 2017, which aimed to bring together a highly interdisciplinary community involved in all aspects of genome privacy and security research.
Journal Article
La genética forense y sus aplicaciones en investigación criminal
TL;DR: In fact, polimorfismos nucleotídicos simples (SNPs) van emergiendo como marcadores de future as discussed by the authors, i.e., útiles for muchas aplicaciones específicas, al igual que ocurre con polimorismos in cromosomas sexuales or el ADN mitocondrial.
Journal ArticleDOI
Forensic characteristics and phylogenetic structure of Eastern Chinese Han populations residing along the Yangtze Basin revealed by 19 autosomal STR loci.
TL;DR: The results supported that the 19 autosomal STR loci, which were polymorphic and informative in forensic identification, could also be applied in population genetics studies.
Book ChapterDOI
Forensische Serologie/Molekulare Genetik
D. Patzelt,P. M. Schneider +1 more
TL;DR: In this paper, an individualisierende DNA-Untersuchungen an bei der Obduktion sichergestellten Asservaten (Teile von Leber, Muskulatur, Knochen) durchgefuhrt werden.
Patent
Lateral flow-based nucleic acid sample preparation device, integrated with passive fluid flow control
TL;DR: In this paper, a simplified lateral flow chromatographic nucleic acid sample preparation method, devices, and integrated systems are provided for the efficient concentration of trace samples and the removal of nucleic acids amplification inhibitors.
References
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Journal ArticleDOI
Hypervariable 'minisatellite' regions in human DNA.
TL;DR: A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA ‘fingerprint’ of general use in human genetic analysis.
Book ChapterDOI
The Apportionment of Human Diversity
TL;DR: Lewontin this article pointed out that even in the present era of Darwinism there is considerable diversity of opinion about the amount or importance of intragroup variation as opposed to the variation between races and species.
Journal ArticleDOI
Individual-specific 'fingerprints' of human DNA.
TL;DR: It is shown that other variant (core)n probes can detect additional sets of hypervariable minisatellites to produce somatically stable DNA ‘fingerprints’ which are completely specific to an individual (or to his or her identical twin) and can be applied directly to problems of human identification, including parenthood testing.