Journal ArticleDOI
Encoded evidence: DNA in forensic analysis
Mark A. Jobling,Peter Gill +1 more
TLDR
For example, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases as mentioned in this paper.Abstract:
Sherlock Holmes said "it has long been an axiom of mine that the little things are infinitely the most important", but never imagined that such a little thing, the DNA molecule, could become perhaps the most powerful single tool in the multifaceted fight against crime. Twenty years after the development of DNA fingerprinting, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases.read more
Citations
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Mitochondrial DNA in sensitive forensic analysis.
TL;DR: Evaluation and modifications of existing technologies that are useful in forensic DNA typing, mainly focusing on mtDNA are described, which include several assays that are valuable in forensic genetics for DNA quantification, improved mtDNA analysis, and mtDNA mixture interpretation.
Dissertation
DNA persistence and preservation following environmental insult
TL;DR: The results from field experiments suggested that muscle tissues, if available, should be collected for DNA profiling, since even if degraded, a profile can be obtained, and that the isolation of tissues from insect activity as quickly as possible (even if immediate storage is not possible) may be beneficial for DNA persistence.
Journal ArticleDOI
An in-depth population genetic analysis of forensic short tandem repeat loci in Indonesia
Samantha J. Venables,Dennis McNevin,Runa Daniel,Stephen D. Sarre,R.A.H. van Oorschot,Simon J. Walsh +5 more
TL;DR: Results suggest that a number of the sub-populations, as well as the combined data set, display significant departures from equilibrium, which will assist in forming genetically appropriate sub-population groupings for the purpose of constructing defensible forensic STR databases.
Journal ArticleDOI
Genetic analysis of two STR loci (VWA and TPOX) in the Iranian province of Khuzestan.
Ali Mohammad Foroughmand,Maryam Jari,Seyed Reza Kazeminezhad,Arezu Abdollahi,Leila Ahmadi,Maryam Heidari +5 more
TL;DR: The examined STR loci in this study have proven a relatively high genetic variation in the Iranian population, which could be used for construction of a forensic genetic database for theIranian population.
Book Chapter
Understanding the Role of Forensic DNA: A Primer for Criminologists
TL;DR: This document discusses DNA profiles produced after analysing a sample of genetic material retrieved either from an individual or from a crime scene exhibit, and those regions of a DNA profile that vary greatly between individuals.
References
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Journal ArticleDOI
Hypervariable 'minisatellite' regions in human DNA.
TL;DR: A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA ‘fingerprint’ of general use in human genetic analysis.
Book ChapterDOI
The Apportionment of Human Diversity
TL;DR: Lewontin this article pointed out that even in the present era of Darwinism there is considerable diversity of opinion about the amount or importance of intragroup variation as opposed to the variation between races and species.
Journal ArticleDOI
Individual-specific 'fingerprints' of human DNA.
TL;DR: It is shown that other variant (core)n probes can detect additional sets of hypervariable minisatellites to produce somatically stable DNA ‘fingerprints’ which are completely specific to an individual (or to his or her identical twin) and can be applied directly to problems of human identification, including parenthood testing.