Journal ArticleDOI
Encoded evidence: DNA in forensic analysis
Mark A. Jobling,Peter Gill +1 more
TLDR
For example, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases as mentioned in this paper.Abstract:
Sherlock Holmes said "it has long been an axiom of mine that the little things are infinitely the most important", but never imagined that such a little thing, the DNA molecule, could become perhaps the most powerful single tool in the multifaceted fight against crime. Twenty years after the development of DNA fingerprinting, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases.read more
Citations
More filters
Journal ArticleDOI
Analysis of DNA from degraded tissue
TL;DR: The results suggested that there is a good chance to obtain a full nuclear DNA profile from tissue samples immersed in the water and sea water for a week, however, if tissue samples were left air-dried in open environment over 4 days, there would be a high chance of obtaining an incomplete/ no DNA profile.
Dissertation
Zur Evolution von Short Tandem Repeats
TL;DR: Short Tandem Repeats (STRs) sind DNA-Abschnitte, in denen sich eine kurze Nukleotid-Sequenz aufeinanderfolgend wiederholt wiedERholt, und Mutationen an einigen dieser Loci sind fur bestimmte Krankheiten verantwortlich.
Journal ArticleDOI
Genomic Data Privacy and Security: Where We Stand and Where We Are Heading
TL;DR: This special issue explores the risks of genomic data storage and provides an overview of solutions ensuring the integrity and privacy of genomic computation.
Journal ArticleDOI
On the Forensic Use of Y-Chromosome Polymorphisms
TL;DR: A brief history focusing on the forensic use of Y-chromosome polymorphisms is sketched, describing the various applications of short-tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) on the Y- chromosome.
References
More filters
Journal ArticleDOI
Hypervariable 'minisatellite' regions in human DNA.
TL;DR: A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA ‘fingerprint’ of general use in human genetic analysis.
Book ChapterDOI
The Apportionment of Human Diversity
TL;DR: Lewontin this article pointed out that even in the present era of Darwinism there is considerable diversity of opinion about the amount or importance of intragroup variation as opposed to the variation between races and species.
Journal ArticleDOI
Individual-specific 'fingerprints' of human DNA.
TL;DR: It is shown that other variant (core)n probes can detect additional sets of hypervariable minisatellites to produce somatically stable DNA ‘fingerprints’ which are completely specific to an individual (or to his or her identical twin) and can be applied directly to problems of human identification, including parenthood testing.