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Journal ArticleDOI

Encoded evidence: DNA in forensic analysis

TLDR
For example, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases as mentioned in this paper.
Abstract
Sherlock Holmes said "it has long been an axiom of mine that the little things are infinitely the most important", but never imagined that such a little thing, the DNA molecule, could become perhaps the most powerful single tool in the multifaceted fight against crime. Twenty years after the development of DNA fingerprinting, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases.

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Journal ArticleDOI

Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays.

TL;DR: High-density single nucleotide polymorphism genotyping microarrays are used to demonstrate the ability to accurately and robustly determine whether individuals are in a complex genomic DNA mixture, and suggest future research efforts into assessing the viability of previously sub-optimal DNA sources due to sample contamination.
Journal ArticleDOI

Jasmonate passes muster: a receptor and targets for the defense hormone.

TL;DR: The oxylipin jasmonate (JA) regulates many aspects of growth, development, and environmental responses in plants, particularly defense responses against herbivores and necrotrophic pathogens as mentioned in this paper.
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Genetics and genomics of core short tandem repeat loci used in human identity testing.

TL;DR: The physical location of each STR locus in the human genome is delineated and allele ranges and variants observed in human populations are summarized as are mutation rates observed from parentage testing.
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Improving human forensics through advances in genetics, genomics and molecular biology

TL;DR: Advances in genetics, genomics and molecular biology are likely to improve human forensic case work in the near future, including new molecular approaches for finding individuals previously unknown to investigators, and new molecular methods to support links between forensic sample donors and criminal acts.
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Turning the Page: Advancing Paper-Based Microfluidics for Broad Diagnostic Application.

TL;DR: This review examines the advances in paper-based microfluidic diagnostics for medical diagnosis in the context of global health from 2007 to 2016 and highlights emerging health applications, such as male fertility testing and wearable diagnostics.
References
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Journal ArticleDOI

Identification of bodies from the scene of a mass disaster using DNA amplification of short tandem repeat (STR) loci

TL;DR: The accompanying paper in this issue describes work conducted during a collaborative effort to identify the victims of a mass disaster that occurred on the 19th of April 1993 near Waco, Texas using reference blood samples and family trees and presents the results obtained from 61 Waco bodies.

An introduction of forensic DNA analysis

TL;DR: A short history of DNA TYPING and its applications, including the Frye Standard and the Federal Rules of Evidence RFLP PCR and the State of the Debate.
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Linear mixture analysis: a mathematical approach to resolving mixed DNA samples.

TL;DR: This work introduces a new automated approach to resolving forensic DNA mixtures with a straightforward mathematical approach that can integrate all the quantitative PCR data into a single rapid computation and has application to diverse mixture problems.
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A Comment on 'Propaganda and Indoctrination: a Tentative Concept Analysis' by Pertti Hemanus (Gazette, Vol. 20:4)

TL;DR: Hemdnus as mentioned in this paper argued that indoctrination as a social and psychological process can only operate in the direction of the prevailing hegemony in a society and he defined the concepts "indoctrination" and "hegemonistic values" in such a way that this point becomes logically true.
Journal ArticleDOI

Taking account of peak areas when interpreting mixed DNA profiles.

TL;DR: A logical framework for taking account of peak areas when interpreting mixed DNA STR profiles is established by means of data which have been collected from made up mixtures of known concentrations analyzed at short tandem repeat loci.
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