Journal ArticleDOI
Encoded evidence: DNA in forensic analysis
Mark A. Jobling,Peter Gill +1 more
TLDR
For example, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases as mentioned in this paper.Abstract:
Sherlock Holmes said "it has long been an axiom of mine that the little things are infinitely the most important", but never imagined that such a little thing, the DNA molecule, could become perhaps the most powerful single tool in the multifaceted fight against crime. Twenty years after the development of DNA fingerprinting, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases.read more
Citations
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Journal ArticleDOI
STR sequence variants revealed by Pyrosequencing technology
TL;DR: A total of 18 Y-chromosome and autosomal STRs have been successfully analyzed using Pyrosequencing technology, demonstrating that additional information besides the fragment length can be provided in a forensic DNA investigation by these assays.
Journal ArticleDOI
Evaluation of ArmedXpert software tools, MixtureAce and Mixture Interpretation, to analyze MPS-STR data
TL;DR: In this article , the ArmedXpert software tools, MixtureAce and Mixture Interpretation, were used for the analysis of STR profiles of single-sourced and mixed samples generated by the ForenSeq DNA Signature Prep kit (Verogen).
Mitochondrial DNA Diversity of Saint Vincent and Trinidad and Its Implications for Caribbean Settlement History
TL;DR: Torres et al. as mentioned in this paper conducted analysis of genetic variation in two indigenous communities, the Garifuna of Saint Vincent and the Grenadines and Trinidad and Tobago, two island nations of the Caribbean Lesser Antilles, and found that the predominate haplogroups represented by Trinidadian and Vincentian samples are A2 and C1.
Book ChapterDOI
Correlation of Insects with Forensic Sciences
Mian Sahib Zar,Moli Huang +1 more
TL;DR: This chapter portrays the importance of insects in forensic sciences and highlights that how the insects are used as evidence in the court and how they can assist in solving crimes.
Journal ArticleDOI
DNASF: A Statistical Package to Analyze the Distribution andPolymorphism of CODIS STR Loci in a Heterogeneous Population
TL;DR: DNASF (DNA Statistics for Forensics) is a package of statistical programs designed to analyze the STR distribution in a heterogeneous population and made it a reliable and effective tool for forensic investigations.
References
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Journal ArticleDOI
Hypervariable 'minisatellite' regions in human DNA.
TL;DR: A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA ‘fingerprint’ of general use in human genetic analysis.
Book ChapterDOI
The Apportionment of Human Diversity
TL;DR: Lewontin this article pointed out that even in the present era of Darwinism there is considerable diversity of opinion about the amount or importance of intragroup variation as opposed to the variation between races and species.
Journal ArticleDOI
Individual-specific 'fingerprints' of human DNA.
TL;DR: It is shown that other variant (core)n probes can detect additional sets of hypervariable minisatellites to produce somatically stable DNA ‘fingerprints’ which are completely specific to an individual (or to his or her identical twin) and can be applied directly to problems of human identification, including parenthood testing.