Functional connectome fingerprinting: identifying individuals using patterns of brain connectivity
Emily S. Finn,Xilin Shen,Dustin Scheinost,Monica D. Rosenberg,Jessica S. Huang,Marvin M. Chun,Xenophon Papademetris,R. Todd Constable +7 more
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In this article, the authors show that every individual has a unique pattern of functional connections between brain regions, which act as a fingerprint that can accurately identify the individual from a large group.Abstract:
This study shows that every individual has a unique pattern of functional connections between brain regions. This functional connectivity profile acts as a ‘fingerprint’ that can accurately identify the individual from a large group. Furthermore, an individual's connectivity profile can predict his or her level of fluid intelligence.read more
Citations
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Dynamic Expression of Brain Functional Systems Disclosed by Fine-Scale Analysis of Edge Time Series
TL;DR: It is proposed that functional systems appear transiently and intermittently, and that FC results from the overlay of many variable instances of system expression, a binary decomposition of the original time series that very closely approximates functional connectivity.
Journal ArticleDOI
Toward Robust Anxiety Biomarkers: A Machine Learning Approach in a Large-Scale Sample.
TL;DR: In this study, a suite of neuroimaging-based machine learning models predicting anxiety within a discovery sample and a generalization test within the holdout sample did not find evidence of a generalizable anxiety biomarker.
Journal ArticleDOI
Towards characterizing the regional cerebral perfusion in evaluating the severity of major depression disorder with SPECT/CT
Jinming Li,Jinming Li,Yuan Yang,Yuankai Zhu,Liqiang Zhou,Yunfeng Han,Tao Yin,Zhaoting Cheng,Guopeng Zhang,Yanxia Shen,Jing Chen +10 more
TL;DR: The findings indicated that the rCBF SPECT/CT may provide an objective assessment for MDD severity, and might be used monitoring therapeutic efficacy in the management of MDD.
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The NonHuman Primate Neuroimaging & Neuroanatomy Project
Takuya Hayashi,Yujie Hou,Matthew F. Glasser,Joonas A. Autio,Kenneth Knoblauch,Miho Inoue-Murayama,Tim Coalson,Essa Yacoub,Stephen M. Smith,Henry Kennedy,David C. Van Essen +10 more
TL;DR: The NHP_NNP is acquiring high-resolution structural, functional, and diffusion MRI data together with behavioral measures from over 100 individual macaques and marmosets in order to generate non-invasive measures of brain architecture such as myelin and cortical thickness maps, as well as functional and diffusion tractography-based connectomes.
Journal ArticleDOI
The emergence of a functionally flexible brain during early infancy.
Weiyan Yin,Tengfei Li,Sheng-Che Hung,Han Zhang,Li Wang,Dinggang Shen,Hongtu Zhu,Peter J. Mucha,Jessica R. Cohen,Weili Lin +9 more
TL;DR: Results showed that neural flexibility of whole brain, motor, and high-order brain functional networks/regions increased significantly with age, while visual regions exhibited a temporally stable pattern, suggesting spatially and temporally nonuniform developmental features of neural flexibility.
References
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Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain
Nathalie Tzourio-Mazoyer,B. Landeau,D. Papathanassiou,Fabrice Crivello,Octave Etard,Nicolas Delcroix,Bernard Mazoyer,Marc Joliot +7 more
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Mikail Rubinov,Olaf Sporns +1 more
TL;DR: Construction of brain networks from connectivity data is discussed and the most commonly used network measures of structural and functional connectivity are described, which variously detect functional integration and segregation, quantify centrality of individual brain regions or pathways, and test resilience of networks to insult.
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The organization of the human cerebral cortex estimated by intrinsic functional connectivity
B.T. Thomas Yeo,Fenna M. Krienen,Jorge Sepulcre,Jorge Sepulcre,Mert R. Sabuncu,Mert R. Sabuncu,Danial Lashkari,Marisa O. Hollinshead,Marisa O. Hollinshead,Joshua L. Roffman,Jordan W. Smoller,Lilla Zöllei,Jonathan R. Polimeni,Bruce Fischl,Bruce Fischl,Hesheng Liu,Randy L. Buckner +16 more
TL;DR: In this paper, the organization of networks in the human cerebrum was explored using resting-state functional connectivity MRI data from 1,000 subjects and a clustering approach was employed to identify and replicate networks of functionally coupled regions across the cerebral cortex.
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Research domain criteria (RDoC): toward a new classification framework for research on mental disorders
Journal ArticleDOI
Correspondence of the brain's functional architecture during activation and rest.
Stephen M. Smith,Peter T. Fox,Karla L. Miller,David C. Glahn,P. Mickle Fox,Clare E. Mackay,Nicola Filippini,Kate E. Watkins,Roberto Toro,Angela R. Laird,Christian F. Beckmann,Christian F. Beckmann +11 more
TL;DR: It is concluded that the full repertoire of functional networks utilized by the brain in action is continuously and dynamically “active” even when at “rest.”