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Open AccessJournal ArticleDOI

Functional connectome fingerprinting: identifying individuals using patterns of brain connectivity

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TLDR
In this article, the authors show that every individual has a unique pattern of functional connections between brain regions, which act as a fingerprint that can accurately identify the individual from a large group.
Abstract
This study shows that every individual has a unique pattern of functional connections between brain regions. This functional connectivity profile acts as a ‘fingerprint’ that can accurately identify the individual from a large group. Furthermore, an individual's connectivity profile can predict his or her level of fluid intelligence.

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Citations
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Fast and Accurate Detection of Complex Imaging Genetics Associations Based on Greedy Projected Distance Correlation

TL;DR: A novel method to detect conditional associations between imaging genetics data is presented, using projected distance correlation to build a conditional dependency graph among high-dimensional mixed data, and then using multiple testing to detect significant group level associations.
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Whole-Brain Dynamics in Aging: Disruptions in Functional Connectivity and the Role of the Rich Club.

TL;DR: In this paper, the authors employed two data-driven whole-brain approaches based on the phase synchronization of blood-oxygen-level-dependent signals to analyze resting-state fMRI data from 620 subjects divided into two groups (middle-age group (n = 310); age range, 50-64 years versus older group(n = 210); age ranges, 65-91 years).
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Modelling subject variability in the spatial and temporal characteristics of functional modes

TL;DR: Probabilistic functional modes are extended with a hierarchical temporal model and improved spatial sensitivity is demonstrated using rfMRI data from 1000 HCP subjects.
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Local connectome phenotypes predict social, health, and cognitive factors.

TL;DR: This work shows, for the first time, how the local connectome has both the sensitivity and the specificity to be used as a phenotypic marker for subject-specific attributes, and shows how variability in the local connectedome is correlated in a principled way across individuals.
Journal ArticleDOI

Functional connectome fingerprinting accuracy in youths and adults is similar when examined on the same day and 1.5-years apart.

TL;DR: A framework for understanding the sensitivity and specificity of fingerprinting accuracy in adolescents and adults at multiple time scales is provided, suggesting that cognitive and default networks play a primary role in the individualization of one's connectome.
References
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Journal ArticleDOI

Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain

TL;DR: An anatomical parcellation of the spatially normalized single-subject high-resolution T1 volume provided by the Montreal Neurological Institute was performed and it is believed that this tool is an improvement for the macroscopical labeling of activated area compared to labeling assessed using the Talairach atlas brain.
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Complex network measures of brain connectivity: uses and interpretations.

TL;DR: Construction of brain networks from connectivity data is discussed and the most commonly used network measures of structural and functional connectivity are described, which variously detect functional integration and segregation, quantify centrality of individual brain regions or pathways, and test resilience of networks to insult.
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The organization of the human cerebral cortex estimated by intrinsic functional connectivity

TL;DR: In this paper, the organization of networks in the human cerebrum was explored using resting-state functional connectivity MRI data from 1,000 subjects and a clustering approach was employed to identify and replicate networks of functionally coupled regions across the cerebral cortex.
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