GDNF–Induced Activation of the Ret Protein Tyrosine Kinase Is Mediated by GDNFR-α, a Novel Receptor for GDNF
Shuqian Jing,Duanzhi Wen,Yanbin Yu,Paige Holst,Yi Luo,Mei Fang,Rami Tamir,Laarni Antonio,Zheng Hu,Rod Cupples,Jean-Claude Louis,Sylvia Hu,Bruce W. Altrock,Gary M. Fox +13 more
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TLDR
In this paper, the expression cloning and characterization of GDNFR-α, a novel glycosylphosphatidylinositol-linked cell surface receptor for glial cell line-derived neurotrophic factor (GDNF), was reported.About:
This article is published in Cell.The article was published on 1996-06-28 and is currently open access. It has received 1164 citations till now. The article focuses on the topics: Glial cell line-derived neurotrophic factor & GDNF family of ligands.read more
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Multiple endokrine Neoplasie Typ 1 und 2 Diagnostische Leitlinien und molekulare Pathologie 1997
TL;DR: Direct mutational analysis of germline DNA allows for the unambiguous identification of gene carriers and therefore the discrimination of MEN-associated and sporadically occurring neuroendocrine tumors.
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3D-printed hyaluronic acid hydrogel scaffolds impregnated with neurotrophic factors (BDNF, GDNF) for post-traumatic brain tissue reconstruction
Tatiana A. Mishchenko,Maria O. Klimenko,Alisa Kuznetsova,Roman S. Yarkov,A. G. Savelyev,Anastasia V. Sochilina,Alexandra Olegovna Mariyanats,Vladimir K. Popov,Evgeny V. Khaydukov,Andrei V. Zvyagin,Maria Vedunova +10 more
TL;DR: 3D hyaluronic scaffolds impregnated with neurotrophic factors (BDNF, GDNF) possessing 600 kPa Young’s moduli and 336% swelling ratios provide a platform for personalized brain implants stimulating effective morphological and functional recovery of nerve tissue after traumatic brain injury.
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A rapid method for the purification of wild-type and V804M mutant ret catalytic domain: A tool to study thyroid cancer.
Elisa Sala,Luca Mologni,Sara Cazzaniga,Elena Papinutto,Carlo Gambacorti-Passerini,Carlo Gambacorti-Passerini +5 more
TL;DR: In this paper, a recombinant RET kinase domain (rRET) containing the active site, the ATP binding pocket, and the activation loop with regulatory activity, with the Baculovirus expression system was expressed.
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Unique spindle cells in the involved ileal segment of rats with congenital aganglionosis
Yoshio Watanabe,Takahiro Ito,Satoshi Iino,Toru Harada,Hisami Ando,Takahiko Seo,Shigeru Kobayashi,Tsuyoshi Ozaki +7 more
TL;DR: This study showed PGP9.5-positive pacemaker cells in the aganglionic ileal segment in the first time, and these cells may prove to be a maldeveloped microenvironment of agangLionic segment.
References
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TL;DR: A second edition of Antibodies: A Laboratory Manual is being published in September 2013, Revised, extended and updated by Edward Greenfield of the Dana-Farber Cancer Center, the material has been recast with extensive new information and new chapters have been added.
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TL;DR: Cet article synthese montre comment des recepteurs membranaires a activite tyrosine kinase peuvent etre impliques dans la transduction and notamment jouent le role de signal de the transduction.
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