Global cancer statistics
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TLDR
A substantial proportion of the worldwide burden of cancer could be prevented through the application of existing cancer control knowledge and by implementing programs for tobacco control, vaccination, and early detection and treatment, as well as public health campaigns promoting physical activity and a healthier dietary intake.Abstract:
The global burden of cancer continues to increase largely because of the aging and growth of the world population alongside an increasing adoption of cancer-causing behaviors, particularly smoking, in economically developing countries. Based on the GLOBOCAN 2008 estimates, about 12.7 million cancer cases and 7.6 million cancer deaths are estimated to have occurred in 2008; of these, 56% of the cases and 64% of the deaths occurred in the economically developing world. Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females, accounting for 23% of the total cancer cases and 14% of the cancer deaths. Lung cancer is the leading cancer site in males, comprising 17% of the total new cancer cases and 23% of the total cancer deaths. Breast cancer is now also the leading cause of cancer death among females in economically developing countries, a shift from the previous decade during which the most common cause of cancer death was cervical cancer. Further, the mortality burden for lung cancer among females in developing countries is as high as the burden for cervical cancer, with each accounting for 11% of the total female cancer deaths. Although overall cancer incidence rates in the developing world are half those seen in the developed world in both sexes, the overall cancer mortality rates are generally similar. Cancer survival tends to be poorer in developing countries, most likely because of a combination of a late stage at diagnosis and limited access to timely and standard treatment. A substantial proportion of the worldwide burden of cancer could be prevented through the application of existing cancer control knowledge and by implementing programs for tobacco control, vaccination (for liver and cervical cancers), and early detection and treatment, as well as public health campaigns promoting physical activity and a healthier dietary intake. Clinicians, public health professionals, and policy makers can play an active role in accelerating the application of such interventions globally.read more
Citations
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Journal ArticleDOI
Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers
Tingting Wang,Guoxiang Cai,Yunping Qiu,Na Fei,Menghui Zhang,Xiaoyan Pang,Wei Jia,Sanjun Cai,Liping Zhao +8 more
TL;DR: Reduction of butyrate-producing bacteria in the gut microbiota of CRC patients and increase of opportunistic pathogens may constitute a major structural imbalance of gut microbiota in CRC patients.
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Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma.
Masao Omata,Laurentius A. Lesmana,Ryosuke Tateishi,Pei-Jer Chen,Shi-Ming Lin,Haruhiko Yoshida,Masatoshi Kudo,Jeong Min Lee,Byung Ihn Choi,Ronnie T.P. Poon,Shuichiro Shiina,Ann-Lii Cheng,Ji Dong Jia,Shuntaro Obi,Kwang Hyub Han,Wasim Jafri,Pierce K. H. Chow,Seng Gee Lim,Yogesh Chawla,Unggul Budihusodo,Rino Alvani Gani,C. Rinaldi A. Lesmana,Terawan Agus Putranto,Yun Fan Liaw,Shiv Kumar Sarin +24 more
TL;DR: Recommendations on the management of hepatocellular carcinoma were presented at the fourth APASL single topic conference on viral-related HCC at Bali, Indonesia and approved by the participants of the conference.
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TL;DR: In this Review, Drost and Clevers discuss the recent advances in organoid models of cancer and how they can be exploited to drive the translation of basic cancer research into novel patient-specific treatment regimens in the clinic.
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Diabetes Mellitus and Risk of Colorectal Cancer: A Meta-Analysis
TL;DR: A meta-analysis of published data on the association between diabetes and the incidence and mortality of colorectal cancer found that diabetes was associated with an increased risk of colors, compared with no diabetes, and these results were consistent between case-control and cohort studies and between studies conducted in the United States and in Europe.
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Side Population in Human Lung Cancer Cell Lines and Tumors Is Enriched with Stem-like Cancer Cells
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References
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