Journal ArticleDOI
Global malaria mortality between 1980 and 2010: a systematic analysis
Christopher J L Murray,Lisa C. Rosenfeld,Stephen S Lim,Kathryn G. Andrews,Kyle J Foreman,Diana Haring,Nancy Fullman,Mohsen Naghavi,Rafael Lozano,Alan D. Lopez +9 more
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TLDR
The findings show that the malaria mortality burden is larger than previously estimated, especially in adults, and there has been a rapid decrease in malaria mortality in Africa because of the scaling up of control activities supported by international donors.About:
This article is published in The Lancet.The article was published on 2012-02-04. It has received 1440 citations till now. The article focuses on the topics: Malaria & Child mortality.read more
Citations
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Biological assay of a novel quinoxalinone with antimalarial efficacy on Plasmodium yoelii yoelii.
TL;DR: The results obtained in this study showed that the infection outcome of P.Yoelii yoelii-infected mice is affected by VAM2-6 compound by slowing down the parasite replication, retarding the patency time, and increasing their survival time.
Journal ArticleDOI
A systematic review and synthesis of the strengths and limitations of measuring malaria mortality through verbal autopsy.
Samantha Herrera,Yeetey Enuameh,George Adjei,Kenneth Ayuurebobi Ae-Ngibise,Kwaku Poku Asante,Osman Sankoh,Osman Sankoh,Seth Owusu-Agyei,Yazoume Ye +8 more
TL;DR: Given the need for data to measure progress toward the World Health Organization’s Global Technical Strategy for Malaria 2016–2030 goals, the malaria community should define strategies for improving MM estimates, including exploring whether VA tools and methods could be further improved.
Journal ArticleDOI
Epidemiology of Malaria in Latin America and the Caribbean from 1990 to 2009: Systematic Review and Meta-Analysis.
Ariel Bardach,Agustín Ciapponi,Lucila Rey-Ares,Juan Ignacio Rojas,Agustina Mazzoni,Demián Glujovsky,P. Valanzasca,Marina Romano,Natalia Elorriaga,Maria Julia Dantur Juri,Marcos Boulos +10 more
TL;DR: This study represents the first systematic review of the burden of malaria in Latin America and the Caribbean, with data from 21 countries, and shows an annual incidence rate of 409.0 malaria episodes/1000 person-years, considering all ages, which was 40-fold the one estimated from areas with passive surveillance only.
Journal ArticleDOI
Can plant biotechnology help break the HIV-malaria link?
TL;DR: In this article, the authors explore some of the potential contributions of plant biotechnology and its integration into broader multidisciplinary public health programs to combat the two diseases in developing countries.
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Expression of the Essential Kinase PfCDPK1 from Plasmodium falciparum in Toxoplasma gondii Facilitates the Discovery of Novel Antimalarial Drugs
TL;DR: A recombinant strain of Toxoplasma is established and validated and can be used as a surrogate for the discovery and analysis of PfCDPK1-specific inhibitors that can be developed as antimalarials.
References
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Book
The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.
TL;DR: This is the first in a planned series of 10 volumes that will attempt to "summarize epidemiological knowledge about all major conditions and most risk factors" and use historical trends in main determinants to project mortality and disease burden forward to 2020.
Journal ArticleDOI
Artemisinin Resistance in Plasmodium falciparum Malaria
Arjen M. Dondorp,François Nosten,Poravuth Yi,Debashish Das,Aung Phae Phyo,Joel Tarning,Khin Maung Lwin,Frédéric Ariey,Warunee Hanpithakpong,Sue J. Lee,Pascal Ringwald,Kamolrat Silamut,Mallika Imwong,Kesinee Chotivanich,Pharath Lim,Trent Herdman,Sen Sam An,Shunmay Yeung,Pratap Singhasivanon,Nicholas P. J. Day,Niklas Lindegardh,Duong Socheat,Nicholas J. White +22 more
TL;DR: The overall median clearance times were 84 hours (interquartile range, 60 to 96) in Pailin and 48 hours in Wang Pha (P<0.001) in each of the two locations as discussed by the authors.
Journal ArticleDOI
Global, regional, and national causes of child mortality in 2008: a systematic analysis
Robert E. Black,Simon Cousens,Hope L. Johnson,Joy E Lawn,Igor Rudan,Diego G. Bassani,Prabhat Jha,Harry Campbell,Christa L Fischer Walker,Richard E Cibulskis,Thomas P. Eisele,Li Liu,Colin Mathers +12 more
TL;DR: New estimates for 2008 of the major causes of death in children younger than 5 years in 193 countries are reported to help to focus national programmes and donor assistance.
Journal ArticleDOI
The global distribution of clinical episodes of Plasmodium falciparum malaria
TL;DR: It is estimated that there were 515 (range 300–660) million episodes of clinical P. falciparum malaria in 2002, up to 50% higher than those reported by the World Health Organization and 200% higher for areas outside Africa, reflecting the WHO's reliance upon passive national reporting for these countries.
Journal ArticleDOI
Maternal mortality for 181 countries, 1980-2008: a systematic analysis of progress towards Millennium Development Goal 5.
Margaret C. Hogan,Margaret C. Hogan,Kyle J Foreman,Mohsen Naghavi,Stephanie Y. Ahn,Mengru Wang,Susanna M Makela,Alan D. Lopez,Rafael Lozano,Christopher J L Murray +9 more
TL;DR: Although only 23 countries are on track to achieve a 75% decrease in MMR by 2015, countries such as Egypt, China, Ecuador, and Bolivia have been achieving accelerated progress and substantial, albeit varied, progress has been made towards MDG 5.
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Artemisinin Resistance in Plasmodium falciparum Malaria
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