Journal ArticleDOI
Global malaria mortality between 1980 and 2010: a systematic analysis
Christopher J L Murray,Lisa C. Rosenfeld,Stephen S Lim,Kathryn G. Andrews,Kyle J Foreman,Diana Haring,Nancy Fullman,Mohsen Naghavi,Rafael Lozano,Alan D. Lopez +9 more
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TLDR
The findings show that the malaria mortality burden is larger than previously estimated, especially in adults, and there has been a rapid decrease in malaria mortality in Africa because of the scaling up of control activities supported by international donors.About:
This article is published in The Lancet.The article was published on 2012-02-04. It has received 1440 citations till now. The article focuses on the topics: Malaria & Child mortality.read more
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Modelling the relationship between malaria prevalence as a measure of transmission and mortality across age groups
Sammy Khagayi,Sammy Khagayi,Sammy Khagayi,Meghna Desai,Nyaguara Amek,Vincent Were,Eric Donald Onyango,Chris Odero,Kephas Otieno,Godfrey Bigogo,Stephen Munga,Frank Odhiambo,Mary J. Hamel,Simon Kariuki,Aaron M. Samuels,Laurence Slutsker,John E. Gimnig,Penelope Vounatsou,Penelope Vounatsou +18 more
TL;DR: Malaria parasitaemia from cross-sectional surveys was associated with mortality across age groups over 4 to 5 year periods with clinical malaria more strongly associated withortality than parasite prevalence.
Journal ArticleDOI
Malaria in Children.
TL;DR: An overview of pediatric malaria, including its epidemiology, clinical features, diagnosis, treatment, and prevention in travelers, is provided.
Journal Article
Impacts of Bacillus thuringiensis var. israelensis and Bacillus sphaericus insect larvicides on mosquito larval densities in Lusaka, Zambia
TL;DR: The study highlights the potential of larviciding using Bti and Bs for malaria vector control and its integration with indoor residual spraying and insecticide treated nets.
Journal ArticleDOI
Immune Characterization of Plasmodium falciparum Parasites with a Shared Genetic Signature in a Region of Decreasing Transmission
Amy K. Bei,Ababacar Diouf,Kazutoyo Miura,Daniel B. Larremore,Ulf Ribacke,Gregory Tullo,Eli L. Moss,Daniel E. Neafsey,Rachel F. Daniels,Amir E. Zeituni,Iguosadolo Nosamiefan,Sarah K. Volkman,Ambroise D. Ahouidi,Daouda Ndiaye,Tandakha Ndiaye Dieye,Souleymane Mboup,Caroline O. Buckee,Carole A. Long,Dyann F. Wirth +18 more
TL;DR: This work indicates that the CGS parasites in this cluster express similar var genes, more than would be expected by chance in the population, and that there is year-to-year variation in immune recognition of surface antigens on CGS parasite-infected erythrocytes.
Journal ArticleDOI
Expression and Localization of Amorpha-4,11-diene Synthase in Artemisia annua L.
TL;DR: To explore the organ-specific and developmental distributions of ADS, rabbit polyclonal antibodies were raised against recombinant ADS produced in Escherichia coli from the corresponding A. annua cDNA and revealed that ADS was not expressed in all glandular trichomes of mature leaves.
References
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Book
The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.
TL;DR: This is the first in a planned series of 10 volumes that will attempt to "summarize epidemiological knowledge about all major conditions and most risk factors" and use historical trends in main determinants to project mortality and disease burden forward to 2020.
Journal ArticleDOI
Artemisinin Resistance in Plasmodium falciparum Malaria
Arjen M. Dondorp,François Nosten,Poravuth Yi,Debashish Das,Aung Phae Phyo,Joel Tarning,Khin Maung Lwin,Frédéric Ariey,Warunee Hanpithakpong,Sue J. Lee,Pascal Ringwald,Kamolrat Silamut,Mallika Imwong,Kesinee Chotivanich,Pharath Lim,Trent Herdman,Sen Sam An,Shunmay Yeung,Pratap Singhasivanon,Nicholas P. J. Day,Niklas Lindegardh,Duong Socheat,Nicholas J. White +22 more
TL;DR: The overall median clearance times were 84 hours (interquartile range, 60 to 96) in Pailin and 48 hours in Wang Pha (P<0.001) in each of the two locations as discussed by the authors.
Journal ArticleDOI
Global, regional, and national causes of child mortality in 2008: a systematic analysis
Robert E. Black,Simon Cousens,Hope L. Johnson,Joy E Lawn,Igor Rudan,Diego G. Bassani,Prabhat Jha,Harry Campbell,Christa L Fischer Walker,Richard E Cibulskis,Thomas P. Eisele,Li Liu,Colin Mathers +12 more
TL;DR: New estimates for 2008 of the major causes of death in children younger than 5 years in 193 countries are reported to help to focus national programmes and donor assistance.
Journal ArticleDOI
The global distribution of clinical episodes of Plasmodium falciparum malaria
TL;DR: It is estimated that there were 515 (range 300–660) million episodes of clinical P. falciparum malaria in 2002, up to 50% higher than those reported by the World Health Organization and 200% higher for areas outside Africa, reflecting the WHO's reliance upon passive national reporting for these countries.
Journal ArticleDOI
Maternal mortality for 181 countries, 1980-2008: a systematic analysis of progress towards Millennium Development Goal 5.
Margaret C. Hogan,Margaret C. Hogan,Kyle J Foreman,Mohsen Naghavi,Stephanie Y. Ahn,Mengru Wang,Susanna M Makela,Alan D. Lopez,Rafael Lozano,Christopher J L Murray +9 more
TL;DR: Although only 23 countries are on track to achieve a 75% decrease in MMR by 2015, countries such as Egypt, China, Ecuador, and Bolivia have been achieving accelerated progress and substantial, albeit varied, progress has been made towards MDG 5.
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