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Journal ArticleDOI

Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association.

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TLDR
The Statistical Update represents the most up-to-date statistics related to heart disease, stroke, and the cardiovascular risk factors listed in the AHA's My Life Check - Life’s Simple 7, which include core health behaviors and health factors that contribute to cardiovascular health.
Abstract
Each chapter listed in the Table of Contents (see next page) is a hyperlink to that chapter. The reader clicks the chapter name to access that chapter. Each chapter listed here is a hyperlink. Click on the chapter name to be taken to that chapter. Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together in a single document the most up-to-date statistics related to heart disease, stroke, and the cardiovascular risk factors listed in the AHA’s My Life Check - Life’s Simple 7 (Figure1), which include core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure [BP], and glucose control) that contribute to cardiovascular health. The Statistical Update represents …

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Citations
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Journal ArticleDOI

The Association Between Parity and Subsequent Cardiovascular Disease in Women: The Atherosclerosis Risk in Communities Study.

TL;DR: In a diverse U.S. cohort, a history of 5+ live births is associated with CHD risk, specifically, MI, independent of breastfeeding, and having a prior pregnancy and no live birth isassociated with greater CHD and heart failure risk.
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Enhancing Brain Plasticity to Promote Stroke Recovery

TL;DR: Emerging therapies are described, including modern rehabilitation, brain stimulation, cell therapy, brain-computer interfaces, and peripheral nervous transfer, and treatment-induced plasticity, and key evidence from basic studies on the underlying mechanisms is briefly discussed.
Journal ArticleDOI

Liposomes for drug delivery in stroke

TL;DR: This review highlights the potential of liposomes applications for delivery of therapeutic compounds for treating stroke and among the various types of nanomaterials, Liposomes are the most extensively studied due to their biocompatibility, biodegradability, and low toxicity.
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Neprilysin Inhibitors and Bradykinin.

TL;DR: The approval of LCZ696 therapy for HFrEF represents the first approval of long-term neprilysin inhibitor administration, and it remains to be seen whether LCZ637 therapy for other conditions such as hypertension is also accompanied by an acceptable incidence of angioedema.
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Coculture of Endothelial Cells with Human Pluripotent Stem Cell-Derived Cardiac Progenitors Reveals a Differentiation Stage-Specific Enhancement of Cardiomyocyte Maturation.

TL;DR: It is demonstrated that EC incorporation at the CPC stage of CM differentiation expedites CM maturation, leading to cells that may be better suited for in vitro and in vivo applications of hPSC-derived CMs.
References
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Journal ArticleDOI

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial

TL;DR: Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women, and the results indicate that this regimen should not be initiated or continued for primary prevention of CHD.
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Report of the expert committee on the diagnosis and classification of diabetes mellitus

TL;DR: It was deemed essential to develop an appropriate, uniform terminology and a functional, working classification of diabetes that reflects the current knowledge about the disease.
Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
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