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Journal ArticleDOI

Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association.

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TLDR
The Statistical Update represents the most up-to-date statistics related to heart disease, stroke, and the cardiovascular risk factors listed in the AHA's My Life Check - Life’s Simple 7, which include core health behaviors and health factors that contribute to cardiovascular health.
Abstract
Each chapter listed in the Table of Contents (see next page) is a hyperlink to that chapter. The reader clicks the chapter name to access that chapter. Each chapter listed here is a hyperlink. Click on the chapter name to be taken to that chapter. Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together in a single document the most up-to-date statistics related to heart disease, stroke, and the cardiovascular risk factors listed in the AHA’s My Life Check - Life’s Simple 7 (Figure1), which include core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure [BP], and glucose control) that contribute to cardiovascular health. The Statistical Update represents …

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Citations
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Journal ArticleDOI

Microbial Reduction of Cholesterol to Coprostanol: An Old Concept and New Insights

TL;DR: Light is shed on the microbial metabolic pathways related to coprostanol synthesis and current strategies and future directions are highlighted to better characterize these microbial enzymes and pathways.
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CRP Induces NETosis in Heart Failure Patients with or without Diabetes

TL;DR: In vitro, it is confirmed in vitro that CRP induces a concentration-dependent NETs synthesis, which supports mounting evidences on the role of neutrophils in chronic low-grade inflammation associated with HF.
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Perioperative Cardioprotection: General Mechanisms and Pharmacological Approaches.

TL;DR: This review presents the fundamental mechanisms of conditioning strategies and provides an overview of the most recent and relevant findings on different concepts achieving cardioprotection in the experimental setting, specifically emphasizing pharmacological approaches in the perioperative context.
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Nanocarriers for Stroke Therapy: Advances and Obstacles in Translating Animal Studies

TL;DR: Analysis of current literature reveals lipid- and polymer-based DDS as forerunners of DDS for stroke; however, cell membrane-derived vesicles (CMVs) possess the competitive edge due to their innate biocompatibility and superior efficacy.
Journal ArticleDOI

ECG Signal Classification Using Deep Learning Techniques Based on the PTB-XL Dataset.

TL;DR: In this paper, a deep neural network was developed for the automatic classification of primary ECG signals, which was carried out on the data contained in a PTB-XL database, and three neural network architectures were proposed: the first based on the convolutional network, the second on SincNet, and the third on the CNN with additional entropy-based features.
References
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Journal ArticleDOI

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial

TL;DR: Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women, and the results indicate that this regimen should not be initiated or continued for primary prevention of CHD.
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Report of the expert committee on the diagnosis and classification of diabetes mellitus

TL;DR: It was deemed essential to develop an appropriate, uniform terminology and a functional, working classification of diabetes that reflects the current knowledge about the disease.
Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
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