Insect Fat Body: Energy, Metabolism, and Regulation
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TLDR
This review focuses on energy storage and release in insects and summarizes current understanding of the mechanisms underlying these processes in insects.Abstract:
The fat body plays major roles in the life of insects. It is a dynamic tissue involved in multiple metabolic functions. One of these functions is to store and release energy in response to the energy demands of the insect. Insects store energy reserves in the form of glycogen and triglycerides in the adipocytes, the main fat body cell. Insect adipocytes can store a great amount of lipid reserves as cytoplasmic lipid droplets. Lipid metabolism is essential for growth and reproduction and provides energy needed during extended nonfeeding periods. This review focuses on energy storage and release and summarizes current understanding of the mechanisms underlying these processes in insects.read more
Citations
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Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism.
Armand Valsesia,Qiao-Ping Wang,Qiao-Ping Wang,Nele Gheldof,Jérôme Carayol,Hélène Ruffieux,Hélène Ruffieux,Teleri Clark,Victoria Shenton,Lisa J. Oyston,Gregory Lefebvre,Sylviane Metairon,Christian Chabert,Ondine Walter,Polina Mironova,Paulina Lau,Patrick Descombes,Nathalie Viguerie,Dominique Langin,Dominique Langin,Mary-Ellen Harper,Arne Astrup,Wim H. M. Saris,Robert Dent,G. Gregory Neely,Joerg Hager +25 more
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Reproduction–Immunity Trade-Offs in Insects
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Varroa destructor feeds primarily on honey bee fat body tissue and not hemolymph.
Samuel Ramsey,Ronald Ochoa,Gary R. Bauchan,Connor J. Gulbronson,Joseph Mowery,Allen Carson Cohen,David Lim,Judith Joklik,Joseph M. Cicero,James D. Ellis,David J. Hawthorne,Dennis vanEngelsdorp +11 more
TL;DR: The work shows that this parasite is not consuming hemolymph, as has been the accepted view, but damages host bees by consuming fat body, a tissue roughly analogous to the mammalian liver, which strongly suggest that Varroa are exploiting the fat body as their primary source of sustenance.
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The dynamic roles of intracellular lipid droplets: from archaea to mammals
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