Journal ArticleDOI
Overcoming the Incompatibility Challenge in Chemoenzymatic and Multi-Catalytic Cascade Reactions.
TLDR
This Minireview will summarize recent synthetic examples of (chemo)enzymatic cascade reactions and outline promising methods for their spatial control either by using bio-derived or synthetic systems.Abstract:
Multi-catalytic cascade reactions bear a great potential to minimize downstream and purification steps, leading to a drastic reduction of the produced waste. In many examples, the compatibility of chemo- and biocatalytic steps could be easily achieved. Problems associated with the incompatibility of the catalysts and their reactions, however, are very frequent. Cascade-like reactions can hardly occur in this way. One possible solution to combine, in principle, incompatible chemo- and biocatalytic reactions is the defined control of the microenvironment by compartmentalization or scaffolding. Current methods for the control of the microenvironment of biocatalysts go far beyond classical enzyme immobilization and are thus believed to be very promising tools to overcome incompatibility issues and to facilitate the synthetic application of cascade reactions. In this Minireview, we will summarize recent synthetic examples of (chemo)enzymatic cascade reactions and outline promising methods for their spatial control either by using bio-derived or synthetic systems.read more
Citations
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Journal ArticleDOI
Protein-supported transition metal catalysts: Preparation, catalytic applications, and prospects.
TL;DR: A review of protein-supported transition metal catalysts (PTMCs) can be found in this paper , where a wide range of protein supports, including proteins, protein assemblies, protein-polymer conjugates, and cross-linked proteins, are surveyed and compared.
Journal ArticleDOI
Construction of a Bifunctional Pd(0)‐CALB@SiO <sub>2</sub> Hybrid Catalyst for the Synthesis and Arylation of Imidazo[1,2‐a]pyridine in One Pot
TL;DR: In this paper , an efficient strategy for the construction of enzyme-metal biohybrid catalyst [Pd(0)-CALB@SiO2] via encapsulation of Candida antarctica lipase B and Pd( 0) within silica was described.
Book ChapterDOI
Construction of Multistep Catalytic Systems in Protein Assemblies
Hiroyasu Tabe,Takafumi Ueno +1 more
TL;DR: The main challenge in the development of artificial bionanoreactors is controllable immobilization of multiple catalytic components within a single scaffold composed of protein assemblies as mentioned in this paper.
Journal ArticleDOI
Controlled immobilization of a palladium complex/laccase hybrid into a macrocellular siliceous host.
Fangfang Yang,Pierre Rousselot-Pailley,Cendrine Nicoletti,A. Jalila Simaan,Bruno Faure,Elise Courvoisier-Dezord,Agnès Amouric,Yolande Charmasson,Rénal Backov,Thierry Tron,Yasmina Mekmouche +10 more
TL;DR: In this paper , a site-directed immobilization of a hybrid catalyst bearing a biquinoline-based-Pd(II) complex and a robust laccase within cavities of a silica foam to favor veratryl alcohol oxidation was investigated.
References
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Journal Article
Polymer vesicles : Materials science: Soft surfaces
Dennis E. Discher,Adi Eisenberg +1 more
TL;DR: Future applications of polymer vesicles will rely on exploiting unique property-performance relations, but results to date underscore the fact that biologically derived vesicle are but a small subset of what is physically and chemically possible.
Journal ArticleDOI
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Bohdana M. Discher,You-Yeon Won,David S. Ege,James C. Lee,Frank S. Bates,Dennis E. Discher,Daniel A. Hammer +6 more
TL;DR: The results suggest a new class of synthetic thin-shelled capsules based on block copolymer chemistry, and both the membrane bending and area expansion moduli of electroformed polymersomes (polymer-based liposomes) fell within the range of lipid membrane measurements.
Journal ArticleDOI
Synthesis of polycaprolactone: a review
Marianne Labet,Wim Thielemans +1 more
TL;DR: This critical review summarises the different conditions which have been described to synthesise PCL, and gives a broad overview of the different catalytic systems that were used (enzymatic, organic and metal catalyst systems).
Journal ArticleDOI
Industrial Methods for the Production of Optically Active Intermediates
Michael Breuer,Klaus Ditrich,Tilo Habicher,Bernhard Hauer,Maria Kesseler,Rainer Stürmer,Thomas Zelinski +6 more
TL;DR: For the industrial implementation of many transformations alternative methods are available and the advantages of the individual methods will be discussed herein and exemplified by syntheses of relevant compounds.
Journal ArticleDOI
Highly permeable polymeric membranes based on the incorporation of the functional water channel protein Aquaporin Z
TL;DR: The approach followed here may lead to more productive and sustainable water treatment membranes, whereas the variable levels of permeability obtained with different concentrations of AqpZ may provide a key property for drug delivery applications.