scispace - formally typeset
Journal ArticleDOI

Palladium-catalyzed reactions of organic halides with olefins

Richard F. Heck
- 01 Apr 1979 - 
- Vol. 10, Iss: 37, pp 146-151
About
This article is published in Accounts of Chemical Research.The article was published on 1979-04-01. It has received 818 citations till now. The article focuses on the topics: Palladium.

read more

Citations
More filters
Journal ArticleDOI

From Noble Metal to Nobel Prize: Palladium-Catalyzed Coupling Reactions as Key Methods in Organic Synthesis

TL;DR: The coupling protocol for aryl halides with olefins can be considered as a milestone for the development and application of organometallic catalysis in organic synthesis and set the stage for numerous further applications.
Journal ArticleDOI

The Controlled Display of Biomolecules on Nanoparticles: A Challenge Suited to Bioorthogonal Chemistry

TL;DR: This review includes a critical discussion on the design considerations for NP-bioconjugates and the unique challenges associated with chemistry at the biological-nanoscale interface-the liabilities of traditional bioconjugation chemistries being particularly prominent therein.
Journal ArticleDOI

C-H activation: a complementary tool in the total synthesis of complex natural products.

TL;DR: Recently completed total syntheses showcasing creative and ingenious incorporation of C-Hactivation as a strategic manoeuver are compared with their "non-C-H activation" counterparts, illuminating a new paradigm in strategic synthetic design.
References
Related Papers (5)