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Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013

A. Goldhirsch, +57 more
- 01 Sep 2013 - 
- Vol. 24, Iss: 9, pp 2206-2223
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TLDR
The 13th St Gallen International Breast Cancer Conference (2013) Expert Panel reviewed and endorsed substantial new evidence on aspects of the local and regional therapies for early breast cancer, supporting less extensive surgery to the axilla and shorter durations of radiation therapy.
About: 
This article is published in Annals of Oncology.The article was published on 2013-09-01 and is currently open access. It has received 2831 citations till now. The article focuses on the topics: Breast cancer & Adjuvant therapy.

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Adherence to nutrition-based cancer prevention guidelines and breast, prostate and colorectal cancer risk in the MCC-Spain case-control study

Dora Romaguera, +42 more
- 01 Jul 2017 - 
TL;DR: Evaluation of the association between adherence to nutrition‐based guidelines for cancer prevention and prostate, breast and colorectal cancer in the MCC‐Spain case–control study concluded that a great proportion of common cancer cases could be avoided by adopting healthy lifestyle habits.
Journal ArticleDOI

Molecular signatures in breast cancer

Samir Lal, +3 more
- 01 Dec 2017 - 
TL;DR: The approaches that have been used to develop gene expression signatures into currently available diagnostic assays are reviewed, plus the latest work on genome sequencing, the methodologies used in the discovery process of mutational signatures, and the potential of these signatures to impact the clinic are described.
Journal ArticleDOI

Biomarkers of drugs targeting HER-family signalling in cancer.

Filippo Montemurro, +1 more
- 01 Jan 2014 - 
TL;DR: A review of the value of promising biomarkers of drugs targeting HER‐family receptor targeting on breast cancer and gastric cancer, where HER2 targeting has emerged recently as a successful strategy.
Journal ArticleDOI

Immunohistochemistry for diagnosis and prognosis of breast cancer: a review.

T Bonacho, +2 more
- 01 Feb 2020 - 
TL;DR: Immunohistochemistry can be used to evaluate central prognostic and predictive factors including molecular subtypes, HER2, hormone receptors, proliferation markers (Ki-67) and lymph-vascular invasion markers including ERG, CD31, CD34, factor VIII and podoplanin.
Journal ArticleDOI

Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

Wilbert Zwart, +3 more
- 21 Jul 2015 - 
TL;DR: The tissue-selective side effects of endocrine therapies and specifically their impact on cognitive function, on the basis of clinical data are discussed; the neurobiological effects ofendocrine therapies as observed in preclinical models are also discussed.
References
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Journal ArticleDOI

Comprehensive molecular portraits of human breast tumours

Daniel C. Koboldt, +355 more
- 04 Oct 2012 - 
TL;DR: The ability to integrate information across platforms provided key insights into previously defined gene expression subtypes and demonstrated the existence of four main breast cancer classes when combining data from five platforms, each of which shows significant molecular heterogeneity.
Journal ArticleDOI

Comprehensive molecular portraits of human breast tumours

A. McCullough
- 01 Jan 2013 - 
Journal ArticleDOI

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

Joel S. Parker, +19 more
- 10 Mar 2009 - 
TL;DR: D diagnosis by intrinsic subtype adds significant prognostic and predictive information to standard parameters for patients with breast cancer.
Journal ArticleDOI

Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011

A. Goldhirsch, +5 more
- 01 Aug 2011 - 
TL;DR: Broad treatment recommendations are presented, recognizing that detailed treatment decisions need to consider disease extent, host factors, patient preferences, and social and economic constraints.
Journal ArticleDOI

Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: A randomized clinical trial

Armando E. Giuliano, +9 more
- 09 Feb 2011 - 
TL;DR: Among patients with limited SLN metastatic breast cancer treated with breast conservation and systemic therapy, the use of SLND alone compared with ALND did not result in inferior survival, and overall survival was the primary end point, with a noninferiority margin of a 1-sided hazard ratio of less than 1.3 indicating thatSLND alone is noninherited.
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