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Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013

A. Goldhirsch, +57 more
- 01 Sep 2013 - 
- Vol. 24, Iss: 9, pp 2206-2223
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TLDR
The 13th St Gallen International Breast Cancer Conference (2013) Expert Panel reviewed and endorsed substantial new evidence on aspects of the local and regional therapies for early breast cancer, supporting less extensive surgery to the axilla and shorter durations of radiation therapy.
About: 
This article is published in Annals of Oncology.The article was published on 2013-09-01 and is currently open access. It has received 2831 citations till now. The article focuses on the topics: Breast cancer & Adjuvant therapy.

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Journal ArticleDOI

Influence of Obesity on Breast Density Reduction by Omega-3 Fatty Acids: Evidence from a Randomized Clinical Trial

Narinder Sandhu, +16 more
- 01 Apr 2016 - 
TL;DR: The results suggest that obese women may preferentially experience breast cancer risk reduction from n-3FA administration, and the prespecified hypothesis that body mass index (BMI) influences the relationship between plasma n- 3FA on BD is tested.
Journal ArticleDOI

Differences in biological features of breast cancer between Caucasian (Italian) and African (Tanzanian) populations

Dino Amadori, +10 more
- 23 Mar 2014 - 
TL;DR: The results show that histopathological and biomolecular characteristics in Tanzanian and Italian breast cancers differ substantially, and the high frequency of poorly differentiated, ER-negative, highly proliferating tumors, together with advanced stage at presentation, could be the main prognostic factors linked to the high mortality rates for breast cancer in the African population.
Journal ArticleDOI

Liquid biopsy for breast cancer using extracellular vesicles and cell-free microRNAs as biomarkers.

Patricia Midori Murobushi Ozawa, +5 more
- 13 May 2020 - 
TL;DR: New findings about c-miRNA and their potential as biomarkers for BC diagnosis, prognosis, and therapy are discussed and the impact of limitations associated with the standardization of analysis techniques and methods on the implementation of these biomarkers in the clinical setting is addressed.
Journal ArticleDOI

Intravoxel incoherent motion magnetic resonance imaging for breast cancer: A comparison with benign lesions and evaluation of heterogeneity in different tumor regions with prognostic factors and molecular classification

Ming Zhao, +8 more
- 01 Oct 2018 - 
TL;DR: The IVIM parameters of tumor, tumor edge and peritumor tissues in various subtypes of breast cancer may be useful for differentiation of Breast cancer subtypes and to assess the invasive extent of the tumors.
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Pathological profiles and clinical management challenges of breast cancer emerging in young women in Indonesia: a hospital-based study.

Sumadi Lukman Anwar, +10 more
- 06 Feb 2019 - 
TL;DR: A high frequency of young breast cancer with biologically more aggressive tumors, late diagnosis, frequent relapse, and poor prognosis is found.
References
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Journal ArticleDOI

Comprehensive molecular portraits of human breast tumours

Daniel C. Koboldt, +355 more
- 04 Oct 2012 - 
TL;DR: The ability to integrate information across platforms provided key insights into previously defined gene expression subtypes and demonstrated the existence of four main breast cancer classes when combining data from five platforms, each of which shows significant molecular heterogeneity.
Journal ArticleDOI

Comprehensive molecular portraits of human breast tumours

A. McCullough
- 01 Jan 2013 - 
Journal ArticleDOI

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

Joel S. Parker, +19 more
- 10 Mar 2009 - 
TL;DR: D diagnosis by intrinsic subtype adds significant prognostic and predictive information to standard parameters for patients with breast cancer.
Journal ArticleDOI

Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011

A. Goldhirsch, +5 more
- 01 Aug 2011 - 
TL;DR: Broad treatment recommendations are presented, recognizing that detailed treatment decisions need to consider disease extent, host factors, patient preferences, and social and economic constraints.
Journal ArticleDOI

Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: A randomized clinical trial

Armando E. Giuliano, +9 more
- 09 Feb 2011 - 
TL;DR: Among patients with limited SLN metastatic breast cancer treated with breast conservation and systemic therapy, the use of SLND alone compared with ALND did not result in inferior survival, and overall survival was the primary end point, with a noninferiority margin of a 1-sided hazard ratio of less than 1.3 indicating thatSLND alone is noninherited.
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