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Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013

A. Goldhirsch, +57 more
- 01 Sep 2013 - 
- Vol. 24, Iss: 9, pp 2206-2223
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TLDR
The 13th St Gallen International Breast Cancer Conference (2013) Expert Panel reviewed and endorsed substantial new evidence on aspects of the local and regional therapies for early breast cancer, supporting less extensive surgery to the axilla and shorter durations of radiation therapy.
About: 
This article is published in Annals of Oncology.The article was published on 2013-09-01 and is currently open access. It has received 2831 citations till now. The article focuses on the topics: Breast cancer & Adjuvant therapy.

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Journal ArticleDOI

Personalized medicine: Present and future of breast cancer management

Renaud Sabatier, +2 more
- 01 Sep 2014 - 
TL;DR: The advances in treatment personalization which are currently used in daily practice as well as the technologies and therapies under investigation in various clinical trials are presented.
Journal ArticleDOI

No breast cancer subgroup can be spared postoperative radiotherapy after breast-conserving surgery. Fifteen-year results from the Swedish Breast Cancer Group randomised trial, SweBCG 91 RT.

Fredrika Killander, +8 more
- 01 Nov 2016 - 
TL;DR: Good predictive markers for radiation sensitivity and improved adjuvant systemic therapy are needed to omit RT after BCS, which significantly reduced the incidence of IBTR at 15 years of follow-up.
Journal ArticleDOI

Performance of Three-Biomarker Immunohistochemistry for Intrinsic Breast Cancer Subtyping in the AMBER Consortium

Emma H. Allott, +21 more
- 01 Mar 2016 - 
TL;DR: Three-biomarker IHC-based subtyping has reasonable accuracy for distinguishing basal-like from nonbasal-like, although additional biomarkers are required for accurate classification of luminal A, luminal B, and HER2-enriched cancers.
Journal ArticleDOI

Impact of Oncotype DX breast Recurrence Score testing on adjuvant chemotherapy use in early breast cancer: Real world experience in Greater Manchester, UK.

J. Loncaster, +7 more
- 01 May 2017 - 
TL;DR: In this paper, the authors evaluated the impact of Oncotype DX ® Breast Recurrence Score (RS) assay on adjuvant chemotherapy decision-making in routine clinical practice in a UK Cancer Network.
Journal ArticleDOI

Comparison of the Diagnostic Accuracy of Magnetic Resonance Imaging with Sonography in the Prediction of Breast Cancer Tumor Size: A Concordance Analysis with Histopathologically Determined Tumor Size

Hung-Wen Lai, +7 more
- 24 Feb 2015 - 
TL;DR: MRI tends to overestimate the actual tumor size, while sonography frequently underestimates it, and combined sonography and MRI increases the accuracy of tumor size prediction.
References
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Journal ArticleDOI

Comprehensive molecular portraits of human breast tumours

Daniel C. Koboldt, +355 more
- 04 Oct 2012 - 
TL;DR: The ability to integrate information across platforms provided key insights into previously defined gene expression subtypes and demonstrated the existence of four main breast cancer classes when combining data from five platforms, each of which shows significant molecular heterogeneity.
Journal ArticleDOI

Comprehensive molecular portraits of human breast tumours

A. McCullough
- 01 Jan 2013 - 
Journal ArticleDOI

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

Joel S. Parker, +19 more
- 10 Mar 2009 - 
TL;DR: D diagnosis by intrinsic subtype adds significant prognostic and predictive information to standard parameters for patients with breast cancer.
Journal ArticleDOI

Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011

A. Goldhirsch, +5 more
- 01 Aug 2011 - 
TL;DR: Broad treatment recommendations are presented, recognizing that detailed treatment decisions need to consider disease extent, host factors, patient preferences, and social and economic constraints.
Journal ArticleDOI

Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: A randomized clinical trial

Armando E. Giuliano, +9 more
- 09 Feb 2011 - 
TL;DR: Among patients with limited SLN metastatic breast cancer treated with breast conservation and systemic therapy, the use of SLND alone compared with ALND did not result in inferior survival, and overall survival was the primary end point, with a noninferiority margin of a 1-sided hazard ratio of less than 1.3 indicating thatSLND alone is noninherited.
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