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Polymers for 3D Printing and Customized Additive Manufacturing

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TLDR
Polymers are by far the most utilized class of materials for AM and their design, additives, and processing parameters as they relate to enhancing build speed and improving accuracy, functionality, surface finish, stability, mechanical properties, and porosity are addressed.
Abstract
Additive manufacturing (AM) alias 3D printing translates computer-aided design (CAD) virtual 3D models into physical objects. By digital slicing of CAD, 3D scan, or tomography data, AM builds objects layer by layer without the need for molds or machining. AM enables decentralized fabrication of customized objects on demand by exploiting digital information storage and retrieval via the Internet. The ongoing transition from rapid prototyping to rapid manufacturing prompts new challenges for mechanical engineers and materials scientists alike. Because polymers are by far the most utilized class of materials for AM, this Review focuses on polymer processing and the development of polymers and advanced polymer systems specifically for AM. AM techniques covered include vat photopolymerization (stereolithography), powder bed fusion (SLS), material and binder jetting (inkjet and aerosol 3D printing), sheet lamination (LOM), extrusion (FDM, 3D dispensing, 3D fiber deposition, and 3D plotting), and 3D bioprinting....

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Additive manufacturing (3D printing): A review of materials, methods, applications and challenges

TL;DR: A comprehensive review of the main 3D printing methods, materials and their development in trending applications was carried out in this paper, where the revolutionary applications of AM in biomedical, aerospace, buildings and protective structures were discussed.

Organ Printing: Tissue Spheroids as Building Blocks

TL;DR: Organ printing can be defined as layer-by-layer additive robotic biofabrication of three-dimensional functional living macrotissues and organ constructs using tissue spheroids as building blocks.
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Photopolymerization in 3D Printing

TL;DR: The field of 3D printing is continuing its rapid development in both academic and industrial research environments as mentioned in this paper, which offers flexibility over the final properties of the 3D printed materials (such as optical, chemical and mechanical properties) using versatile polymer chemistry.
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Biofabrication strategies for 3D in vitro models and regenerative medicine

TL;DR: This Review examines biofabrication strategies for the construction of functional tissue replacements and organ models, focusing on the development of biomaterials, such as supramolecular and photosensitive materials, that can be processed using bioFabrication techniques.
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3D printing of hydrogels: Rational design strategies and emerging biomedical applications

TL;DR: A review of hydrogel-based biomaterial inks and bioinks for 3D printing can be found in this paper, where the authors provide a comprehensive overview and discussion of the tailorability of material, mechanical, physical, chemical and biological properties.
References
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Journal ArticleDOI

Elastic Fully Three-dimensional Microstructure Scaffolds for Cell Force Measurements

TL;DR: It is shown that biocompatible scaffolds can be fabricated by means of direct laser writing (DLW) and subsequent surface functionalization and it is demonstrated that these scaffolding can be rhythmically deformed by single beating cardiomyocytes.
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Design and fabrication of cast orthopedic implants with freeform surface textures from 3‐D printed ceramic shell

TL;DR: 3D printing was applied to the fabrication of sub-millimeter surface textures with overhang and undercut geometries for use in orthopedic prostheses as bony ingrowth structures as well as to fabricate ceramic molds of alumina powder and silica binder.
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Recycling of polyamide 12 based powders in the laser sintering process

TL;DR: In this paper, the authors investigate the polyamide 12 (PA12) powder properties deterioration in the laser sintering (LS) process and propose a methodology for more efficient powder recycling.
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Clinical microneedle injection of methyl nicotinate: stratum corneum penetration

TL;DR: This work comparesmicroneedle injections with topical application (TA) to investigate if microneedles enhance in vivo drug delivery past the stratum corneum.
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Food Layered Manufacture: A new process for constructing solid foods

TL;DR: Additive manufacturing is a digitally-controlled, robotic construction process which builds up complex solid forms layer by layer, applying phase transitions or chemical reactions to fuse layers together as discussed by the authors.However, the construction of predictable structures by FLM requires a first-principles, materials science approach to formulation design.
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