Risk factors for respiratory syncytial virus associated with acute lower respiratory infection in children under five years: Systematic review and meta-analysis.
Ting Shi,Evelyn Balsells,Elizabeth Wastnedge,Rosalyn J. Singleton,Zeba A Rasmussen,Heather J. Zar,Barbara Rath,Shabir A. Madhi,Stuart Campbell,Linda Cheyenne Vaccari,Lisa R. Bulkow,Elizabeth D. Thomas,Whitney Barnett,Christian Hoppe,Harry Campbell,Harish Nair +15 more
TLDR
In addition to the future impact of novel RSV vaccines, national action against ALRI risk factors as part of national control programmes can be expected to reduce burden of disease from RSV.Abstract:
Background
Respiratory syncytial virus (RSV) is the most common pathogen identified in young children with acute lower respiratory infection (ALRI) as well as an important cause of hospital admission. The high incidence of RSV infection and its potential severe outcome make it important to identify and prioritise children who are at higher risk of developing RSV–associated ALRI. We aimed to identify risk factors for RSV–associated ALRI in young children.read more
Citations
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Journal ArticleDOI
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study
Ting Shi,David A. McAllister,Katherine L. O'Brien,Eric A. F. Simões,Shabir A. Madhi,Bradford D. Gessner,Fernando P. Polack,Evelyn Balsells,Sozinho Acácio,Claudia Aguayo,Issifou Alassani,Asad Ali,Martin Antonio,Shally Awasthi,Juliet O. Awori,Eduardo Azziz-Baumgartner,Eduardo Azziz-Baumgartner,Henry C. Baggett,Vicky L. Baillie,Angel Balmaseda,Alfredo Barahona,Sudha Basnet,Sudha Basnet,Quique Bassat,Quique Bassat,Wilma Basualdo,Godfrey Bigogo,Louis Bont,Robert F. Breiman,W. Abdullah Brooks,W. Abdullah Brooks,Shobha Broor,Nigel Bruce,Dana Bruden,Philippe Buchy,Stuart Campbell,Phyllis Carosone-Link,Mandeep S. Chadha,James Chipeta,Monidarin Chou,Wilfrido Clara,Cheryl Cohen,Cheryl Cohen,Elizabeth de Cuellar,Duc Anh Dang,Budragchaagiin Dash-Yandag,Maria Deloria-Knoll,Mukesh Dherani,Tekchheng Eap,Bernard E. Ebruke,Marcela Echavarria,Carla Cecília de Freitas Lázaro Emediato,Rodrigo Fasce,Daniel R. Feikin,Luzhao Feng,Angela Gentile,Aubree Gordon,Doli Goswami,Doli Goswami,Sophie Goyet,Michelle J. Groome,Natasha B. Halasa,Siddhivinayak Hirve,Nusrat Homaira,Nusrat Homaira,Stephen R. C. Howie,Stephen R. C. Howie,Stephen R. C. Howie,Jorge Jara,Imane Jroundi,Cissy B. Kartasasmita,Najwa Khuri-Bulos,Karen L. Kotloff,Anand Krishnan,Romina Libster,Romina Libster,Olga Lopez,Marilla G. Lucero,Florencia Lución,Socorro Lupisan,Debora N. Marcone,John P. McCracken,Mario Mejia,Jennifer C. Moïsi,Joel M. Montgomery,David P. Moore,Cinta Moraleda,Jocelyn Moyes,Jocelyn Moyes,Patrick K. Munywoki,Patrick K. Munywoki,Kuswandewi Mutyara,Mark P. Nicol,D. James Nokes,D. James Nokes,Pagbajabyn Nymadawa,Maria Tereza da Costa Oliveira,Histoshi Oshitani,Nitin Pandey,Gláucia Paranhos-Baccalà,Lia Neu Phillips,Valentina Picot,Mustafizur Rahman,Mala Rakoto-Andrianarivelo,Zeba A Rasmussen,Barbara Rath,Annick Robinson,Candice Romero,Graciela Russomando,Vahid Salimi,Pongpun Sawatwong,Nienke M Scheltema,Brunhilde Schweiger,J. Anthony G. Scott,J. Anthony G. Scott,Phil Seidenberg,Kunling Shen,Rosalyn J. Singleton,Rosalyn J. Singleton,Viviana Sotomayor,Tor A. Strand,Tor A. Strand,Agustinus Sutanto,Mariam Sylla,Milagritos D. Tapia,Somsak Thamthitiwat,Elizabeth Thomas,Rafal Tokarz,Claudia Turner,Marietjie Venter,Sunthareeya Waicharoen,Jianwei Wang,Wanitda Watthanaworawit,Lay-Myint Yoshida,Hongjie Yu,Heather J. Zar,Harry Campbell,Harish Nair,Harish Nair +138 more
TL;DR: In this paper, the authors estimated the incidence and hospital admission rate of RSV-associated acute lower respiratory infection (RSV-ALRI) in children younger than 5 years stratified by age and World Bank income regions.
Journal ArticleDOI
Respiratory syncytial virus hospitalization and mortality: Systematic review and meta-analysis
Renato T. Stein,Louis Bont,Heather J. Zar,Fernando P. Polack,Caroline Park,Ami Claxton,Gerald Borok,Yekaterina Butylkova,Colleen Wegzyn +8 more
TL;DR: The data affirm the importance of RSV disease in the causation of hospitalization and as a significant contributor to pediatric mortality and further demonstrate gestational age as a critical determinant of disease severity.
Journal ArticleDOI
Birth weight in relation to health and disease in later life: an umbrella review of systematic reviews and meta-analyses
Lazaros Belbasis,Makrina D. Savvidou,Chidimma Kanu,Evangelos Evangelou,Evangelos Evangelou,Ioanna Tzoulaki,Ioanna Tzoulaki +6 more
TL;DR: There is weak evidence that birth weight constitutes an effective public health intervention marker and the range of outcomes convincingly associated with birth weight might be narrower than originally described under the “fetal origin hypothesis” of disease.
Journal ArticleDOI
Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants
TL;DR: Nirsevimab as mentioned in this paper is a monoclonal antibody to the RSV fusion protein that has an extended half-life, which is used to prevent RSV infection in healthy late-preterm and term infants.
Journal ArticleDOI
The role of social determinants of health in the risk and prevention of group A streptococcal infection, acute rheumatic fever and rheumatic heart disease: A systematic review
TL;DR: The majority of studies assessing crowding, dwelling characteristics, education and employment status of parents or cases, and nutrition, reported a positive association with risk of GAS infection, ARF or RHD and Crowding and socioeconomic status satisfactorily met the criteria of a causal association.
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Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis
Harish Nair,Harish Nair,D. James Nokes,D. James Nokes,Bradford D. Gessner,Mukesh Dherani,Shabir A. Madhi,Rosalyn J. Singleton,Katherine L. O'Brien,Anna Roca,Anna Roca,Peter F. Wright,Nigel Bruce,Aruna Chandran,Evropi Theodoratou,Agustinus Sutanto,Endang R. Sedyaningsih,Mwanajuma Ngama,Patrick K. Munywoki,Cissy B. Kartasasmita,Eric A. F. Simões,Igor Rudan,Igor Rudan,Martin Weber,Harry Campbell +24 more
TL;DR: Mortality data suggest that RSV is an important cause of death in childhood from ALRI, after pneumococcal pneumonia and Haemophilus influenzae type b, and the development of novel prevention and treatment strategies should be accelerated as a priority.
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Global burden of childhood pneumonia and diarrhoea
Christa L Fischer Walker,Igor Rudan,Li Liu,Harish Nair,Harish Nair,Evropi Theodoratou,Zulfiqar A Bhutta,Katherine L. O'Brien,Harry Campbell,Robert E. Black +9 more
TL;DR: The epidemiology of childhood diarrhoea and that of pneumonia overlap, which might be partly because of shared risk factors, such as undernutrition, suboptimum breastfeeding, and zinc deficiency, and action is needed globally and at country level to accelerate the reduction.
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Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study
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