The ABC gene family in arthropods: Comparative genomics and role in insecticide transport and resistance
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TLDR
A thorough phylogenetic analysis of the seven arthropod and human ABC protein subfamilies is conducted, to infer orthologous relationships that might suggest conserved function of ABC transporters in arthropods.About:
This article is published in Insect Biochemistry and Molecular Biology.The article was published on 2014-02-01 and is currently open access. It has received 442 citations till now. The article focuses on the topics: ATP-binding cassette transporter.read more
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Book ChapterDOI
Diversity of bacillus thuringiensis crystal toxins and mechanism of action
TL;DR: The remarkable progress made in the past 20 years in discovering novel Cry toxins and in elucidating complex mechanisms of Cry and Cyt toxin action are reviewed; subjects relevant to the long-term control of insects that damage crops and vector human disease.
Journal ArticleDOI
Genomic adaptation to polyphagy and insecticides in a major East Asian noctuid pest
Tingcai Cheng,Jiaqi Wu,Wu Yuqian,Rajendra V. E. Chilukuri,Lihua Huang,Kohji Yamamoto,Li Feng,Wanshun Li,Zhiwei Chen,Huizhen Guo,Jianqiu Liu,Shenglong Li,Xiaoxiao Wang,Li Peng,Duolian Liu,Youbing Guo,Bohua Fu,Zhiqing Li,Chun Liu,Yuhui Chen,Archana Tomar,Frédérique Hilliou,Nicolas Montagné,Emmanuelle Jacquin-Joly,Emmanuelle d'Alençon,Rakesh Kumar Seth,Raj K. Bhatnagar,Akiya Jouraku,Takahiro Shiotsuki,Keiko Kadono-Okuda,Amornrat Promboon,Guy Smagghe,Guy Smagghe,Kallare P. Arunkumar,Hirohisa Kishino,Marian R. Goldsmith,Qili Feng,Qingyou Xia,Kazuei Mita +38 more
TL;DR: The gene families encoding receptors for bitter or toxic substances and detoxification enzymes, such as cytochrome P450, carboxylesterase and glutathione-S-transferase were massively expanded in this polyphagous species, enabling its extraordinary ability to detect and detoxify many plant secondary compounds.
Journal ArticleDOI
Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution
Xiao-Guang Chen,Xuanting Jiang,Jinbao Gu,Meng Xu,Yang Wu,Yuhua Deng,Chi Zhang,Mariangela Bonizzoni,Mariangela Bonizzoni,Wannes Dermauw,John Vontas,John Vontas,Peter Armbruster,Xin Huang,Yulan Yang,Hao Zhang,Weiming He,Hong-Juan Peng,Yongfeng Liu,Kun Wu,Jiahua Chen,Manolis Lirakis,Pantelis Topalis,Thomas Van Leeuwen,Thomas Van Leeuwen,Andrew Brantley Hall,Xiaofang Jiang,Chevon N. Thorpe,Rachel Lockridge Mueller,Cheng Sun,Robert M. Waterhouse,Guiyun Yan,Guiyun Yan,Zhijian Jake Tu,Xiaodong Fang,Anthony A. James +35 more
TL;DR: The Aedes albopictus Foshan strain has a large genome with significant population-based size variation, the largest mosquito genome sequenced to date, and its size results principally from an abundance of repetitive DNA classes.
Journal ArticleDOI
Xenobiotic detoxification pathways in honey bees
May R. Berenbaum,Reed M. Johnson +1 more
TL;DR: The western honey bee Apis mellifera has a deficit of detoxification genes spanning Phase I (functionalization), II (conjugation) and III (excretion) gene families, which may render them vulnerable to synergistic interactions among xenobiotics.
Journal ArticleDOI
Mechanisms and ecological consequences of plant defence induction and suppression in herbivore communities.
Merijn R. Kant,Wim Jonckheere,Bram Knegt,Felipe Lemos,Jie Liu,Bernardus C. J. Schimmel,Carlos A. Villarroel,Lívia Maria Silva Ataíde,Wannes Dermauw,Joris J. Glas,Martijn Egas,Arne Janssen,T. G. van Leeuwen,Robert C. Schuurink,Maurice W. Sabelis,Juan M. Alba +15 more
TL;DR: Herbivores have evolved diverse strategies to decrease the negative effects of plant defences in order to maximize the conversion of plant material into offspring, and the ability to suppress induced plant defences appears to occur across plant parasites from different kingdoms.
References
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Frederick R. Blattner,Guy Plunkett,Craig A. Bloch,Nicole T. Perna,Valerie Burland,Monica Riley,Julio Collado-Vides,Jeremy D. Glasner,Christopher K. Rode,George F. Mayhew,Jason Gregor,Nelson Wayne Davis,Heather A. Kirkpatrick,Michael A. Goeden,Debra J. Rose,Bob Mau,Ying Shao +16 more
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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
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TL;DR: The findings explain some of the side effects in patients treated with a combination of carcinostatics and P-glycoprotein inhibitors and indicate that these inhibitors might be useful in selectively enhancing the access of a range of drugs to the brain.
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