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Bas Teusink
Researcher at VU University Amsterdam
Publications - 208
Citations - 12497
Bas Teusink is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Metabolic network & Saccharomyces cerevisiae. The author has an hindex of 56, co-authored 193 publications receiving 10872 citations. Previous affiliations of Bas Teusink include University of Amsterdam & Delft University of Technology.
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Journal ArticleDOI
Lost in Transition: Start-Up of Glycolysis Yields Subpopulations of Nongrowing Cells
Johan H. van Heerden,Johan H. van Heerden,Johan H. van Heerden,Meike T. Wortel,Meike T. Wortel,Meike T. Wortel,Frank J. Bruggeman,Frank J. Bruggeman,Joseph J. Heijnen,Yves J. M. Bollen,Robert Planqué,Josephus Hulshof,Tom O'Toole,S. Aljoscha Wahl,Bas Teusink,Bas Teusink,Bas Teusink +16 more
TL;DR: How cell fate can be determined by glycolytic dynamics combined with cell heterogeneity purely at the metabolic level is revealed, extending fundamental knowledge of this central pathway that is dysfunctional in diseases such as diabetes and cancer.
Journal ArticleDOI
MEMOTE for standardized genome-scale metabolic model testing
Christian Lieven,Moritz Emanuel Beber,Brett G. Olivier,Frank Bergmann,Meriç Ataman,Parizad Babaei,Jennifer A. Bartell,Lars M. Blank,Siddharth Chauhan,Kevin Correia,Christian Diener,Christian Diener,Andreas Dräger,Birgitta E. Ebert,Birgitta E. Ebert,Janaka N. Edirisinghe,José P. Faria,Adam M. Feist,Adam M. Feist,Georgios Fengos,Ronan M. T. Fleming,Beatriz García-Jiménez,Beatriz García-Jiménez,Vassily Hatzimanikatis,Wout van Helvoirt,Wout van Helvoirt,Christopher S. Henry,Henning Hermjakob,Markus J. Herrgård,Ali Kaafarani,Hyun Uk Kim,Zachary A. King,Steffen Klamt,Edda Klipp,Jasper J. Koehorst,Matthias König,Meiyappan Lakshmanan,Dong-Yup Lee,Dong-Yup Lee,Sang Yup Lee,Sang Yup Lee,Sunjae Lee,Sunjae Lee,Nathan E. Lewis,Filipe Liu,Hongwu Ma,Daniel Machado,Radhakrishnan Mahadevan,Paulo Maia,Adil Mardinoglu,Adil Mardinoglu,Gregory L. Medlock,Jonathan M. Monk,Jens Nielsen,Jens Nielsen,Lars K. Nielsen,Lars K. Nielsen,Juan Nogales,Intawat Nookaew,Intawat Nookaew,Bernhard O. Palsson,Bernhard O. Palsson,Jason A. Papin,Kiran Raosaheb Patil,Mark G. Poolman,Nathan D. Price,Osbaldo Resendis-Antonio,Anne Richelle,Isabel Rocha,Isabel Rocha,Benjamin Sanchez,Benjamin Sanchez,Peter J. Schaap,Rahuman S. Malik Sheriff,Saeed Shoaie,Saeed Shoaie,Nikolaus Sonnenschein,Bas Teusink,Paulo Vilaça,Jon Olav Vik,Judith A. H. Wodke,Joana C. Xavier,Qianqian Yuan,Maksim Zakhartsev,Cheng Zhang +84 more
TL;DR: A community effort to develop a test suite named MEMOTE (for metabolic model tests) to assess GEM quality, and advocate adoption of the latest version of the Systems Biology Markup Language level 3 flux balance constraints (SBML3FBC) package as the primary description and exchange format.
Journal ArticleDOI
The danger of metabolic pathways with turbo design
TL;DR: The ubiquity of pathways that possess an initial activation step, suggests that there might be many more genes that, when deleted, cause rather paradoxical regulation phenotypes (i.e. growth defects caused by enhanced utilization of growth substrate).
Journal ArticleDOI
Reconstructing the metabolic network of a bacterium from its genome
TL;DR: The reconstructed network provides the opportunity to visualize the "omics" data within a relevant biological functional context and thus aids the interpretation of those data.
Journal ArticleDOI
Bet-hedging during bacterial diauxic shift
Ana Solopova,Jordi van Gestel,Franz J. Weissing,Herwig Bachmann,Bas Teusink,Jan Kok,Oscar P. Kuipers +6 more
TL;DR: It is shown that actually only a subpopulation is fit enough to partake in the second growth phase and present an evolutionary model, suggesting that this phenomenon might entail a bet-hedging strategy that helps bacteria adapt to the unexpectedly changing environment.