D
Diego Miranda-Saavedra
Researcher at Spanish National Research Council
Publications - 60
Citations - 8478
Diego Miranda-Saavedra is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Gene & Phosphorylation. The author has an hindex of 38, co-authored 59 publications receiving 7559 citations. Previous affiliations of Diego Miranda-Saavedra include University of Oxford & Genome Institute of Singapore.
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Journal ArticleDOI
Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium
Li-Jun Ma,H. Charlotte van der Does,Katherine A. Borkovich,Jeffrey J. Coleman,Marie Josée Daboussi,Antonio Di Pietro,Marie Dufresne,Michael Freitag,Manfred Grabherr,Bernard Henrissat,Petra M. Houterman,Seogchan Kang,Won-Bo Shim,Charles P. Woloshuk,Xiaohui Xie,Jin-Rong Xu,John F. Antoniw,Scott E. Baker,B. H. Bluhm,Andrew Breakspear,Daren W. Brown,Robert A. E. Butchko,Sinéad B. Chapman,Richard M.R. Coulson,Pedro M. Coutinho,Etienne Danchin,Etienne Danchin,Andrew C. Diener,Liane R. Gale,Donald M. Gardiner,Stephen A. Goff,Kim E. Hammond-Kosack,Karen Hilburn,Aurélie Hua-Van,Wilfried Jonkers,Kemal Kazan,Chinnappa D. Kodira,Michael Koehrsen,Lokesh Kumar,Yong-Hwan Lee,Liande Li,Liande Li,John M. Manners,Diego Miranda-Saavedra,Mala Mukherjee,Gyungsoon Park,Jongsun Park,Sook Young Park,Sook Young Park,Robert H. Proctor,Aviv Regev,M. Carmen Ruiz-Roldán,Divya Sain,Sharadha Sakthikumar,Sean M. Sykes,David C. Schwartz,B. Gillian Turgeon,Ilan Wapinski,Olen C. Yoder,Sarah Young,Qiandong Zeng,Shiguo Zhou,James E. Galagan,Christina A. Cuomo,H. Corby Kistler,Martijn Rep +65 more
TL;DR: Comparison of genomes of three phenotypically diverse Fusarium species revealed lineage-specific genomic regions in F. oxysporum that include four entire chromosomes and account for more than one-quarter of the genome, putting the evolution of fungal pathogenicity into a new perspective.
Journal ArticleDOI
The Ectocarpus genome and the independent evolution of multicellularity in brown algae
J. Mark Cock,Lieven Sterck,Pierre Rouzé,Delphine Scornet,Andrew E. Allen,Grigoris D. Amoutzias,Véronique Anthouard,François Artiguenave,Jean-Marc Aury,Jonathan H. Badger,Bank Beszteri,Kenny Billiau,Eric Bonnet,John H. F. Bothwell,Chris Bowler,Catherine Boyen,Colin Brownlee,Carl J. Carrano,Bénédicte Charrier,Ga Youn Cho,Susana M. Coelho,Jonas Collén,Erwan Corre,Corinne Da Silva,Ludovic Delage,Nicolas Delaroque,Simon M. Dittami,Sylvie Doulbeau,Marek Eliáš,Garry Farnham,Claire M. M. Gachon,Bernhard Gschloessl,Svenja Heesch,Kamel Jabbari,Claire Jubin,Hiroshi Kawai,Kei Kimura,Bernard Kloareg,Frithjof C. Küpper,Daniel Lang,Aude Le Bail,Catherine Leblanc,Patrice Lerouge,Martin Lohr,Pascal J. Lopez,Cindy Martens,Florian Maumus,Gurvan Michel,Diego Miranda-Saavedra,Julia Morales,Hervé Moreau,Taizo Motomura,Chikako Nagasato,Carolyn A. Napoli,David R. Nelson,Pi Nyvall-Collén,Akira F. Peters,Cyril Pommier,Philippe Potin,Julie Poulain,Hadi Quesneville,Betsy Read,Stefan A. Rensing,Andrés Ritter,Sylvie Rousvoal,Manoj P. Samanta,Gaelle Samson,Declan C. Schroeder,Béatrice Segurens,Martina Strittmatter,Thierry Tonon,James W. Tregear,Klaus Valentin,Peter von Dassow,Takahiro Yamagishi,Yves Van de Peer,Patrick Wincker +76 more
TL;DR: The Ectocarpus genome sequence represents an important step towards developing this organism as a model species, providing the possibility to combine genomic and genetic approaches to explore these and other aspects of brown algal biology further.
Journal ArticleDOI
Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis
Jane M. Carlton,Robert P. Hirt,Joana C. Silva,Arthur L. Delcher,Michael C. Schatz,Qi Zhao,Jennifer R. Wortman,Shelby L. Bidwell,U. Cecilia M. Alsmark,Sébastien Besteiro,Thomas Sicheritz-Pontén,Christophe Noël,Joel B. Dacks,Peter G. Foster,Cedric Simillion,Yves Van de Peer,Diego Miranda-Saavedra,Geoffrey J. Barton,Gareth D. Westrop,Sylke Müller,Daniele Dessì,Pier Luigi Fiori,Qinghu Ren,Ian T. Paulsen,Hanbang Zhang,Felix D. Bastida-Corcuera,Augusto Simoes-Barbosa,Mark T. Brown,Richard D. Hayes,Mandira Mukherjee,Cheryl Y. M. Okumura,Rachel E. Schneider,Alias J. Smith,Stepanka Vanacova,Maria Villalvazo,Brian J. Haas,Mihaela Pertea,Tamara Feldblyum,T. Utterback,Chung-Li Shu,Kazutoyo Osoegawa,Pieter J. de Jong,Ivan Hrdy,Lenka Horváthová,Zuzana Zubáčová,Pavel Dolezal,Shehre-Banoo Malik,John M. Logsdon,Katrin Henze,Arti Gupta,Ching C. Wang,R. L. Dunne,Jacqueline A. Upcroft,Peter Upcroft,Owen White,Steven L. Salzberg,Petrus Tang,Cheng-Hsun Chiu,Ying-Shiung Lee,T. Martin Embley,Graham H. Coombs,Jeremy C. Mottram,Jan Tachezy,Claire M. Fraser-Liggett,Patricia J. Johnson +64 more
TL;DR: The genome sequence of the protist Trichomonas vaginalis predicts previously unknown functions for the hydrogenosome, which support a common evolutionary origin of this unusual organelle with mitochondria.
Journal ArticleDOI
Draft Genome of the Filarial Nematode Parasite Brugia malayi
Elodie Ghedin,Elodie Ghedin,Shiliang Wang,David J. Spiro,Elisabet Caler,Qi Zhao,Jonathan Crabtree,Jonathan E. Allen,Arthur L. Delcher,David B. Guiliano,Diego Miranda-Saavedra,Samuel V. Angiuoli,Todd Creasy,Paolo Amedeo,Brian J. Haas,Najib M. El-Sayed,Jennifer R. Wortman,Tamara Feldblyum,Luke J. Tallon,Michael C. Schatz,Martin Shumway,Hean Koo,Steven L. Salzberg,Seth Schobel,Mihaela Pertea,Mihai Pop,Owen White,Geoffrey J. Barton,Clotilde K. S. Carlow,Crawford Michael J,Jennifer Daub,Dimmic Matt W,Chris F. Estes,Jeremy M. Foster,Mehul B. Ganatra,William F. Gregory,Nicholas M. Johnson,Jinming Jin,Richard Komuniecki,Ian F Korf,Sanjay Kumar,Sandra J. Laney,Ben-Wen Li,Wen Li,Tim H. Lindblom,Sara Lustigman,Dong Ma,Claude V. Maina,David M. A. Martin,James P. McCarter,Larry A. McReynolds,Makedonka Mitreva,Thomas B. Nutman,John Parkinson,José M. Peregrín-Alvarez,Catherine B. Poole,Qinghu Ren,Lori Saunders,Ann E. Sluder,Katherine A. Smith,Mario Stanke,Thomas R. Unnasch,Jenna Ware,Aguan Wei,Gary J. Weil,Deryck J. Williams,Yinhua Zhang,Steven A. Williams,Claire M. Fraser-Liggett,Barton E. Slatko,Mark Blaxter,Alan L. Scott +71 more
TL;DR: In this article, the authors sequenced the ∼90 megabase (Mb) genome of the human filarial parasite Brugia malayi and predicted ∼11,500 protein coding genes in 71 Mb of robustly assembled sequence.
Journal ArticleDOI
Emerging roles of pseudokinases.
TL;DR: Evidence that the pseudokinase STRAD controls the function of the tumour suppressor kinase LKB1 is reviewed and that a single amino acid substitution within the pseudokerase domain of the tyrosine kinase JAK2 leads to several malignant myeloproliferative disorders.