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Ira Pastan

Researcher at Laboratory of Molecular Biology

Publications -  1304
Citations -  113191

Ira Pastan is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Immunotoxin & Pseudomonas exotoxin. The author has an hindex of 160, co-authored 1286 publications receiving 110069 citations. Previous affiliations of Ira Pastan include Heidelberg University & National Institutes of Health.

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Synthesis and evaluation of a macrocyclic bifunctional chelating agent for use with bismuth radionuclides.

Kayhan Garmestani, +7 more
- 01 May 2001 - 
TL;DR: Results indicate that BF_PEPA appears to not be a suitable bifunctional chelating agent for sequestering isotopes of Bi(III) for radioimmunotherapy applications.
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Energy-dependent calcium uptake by fibroblast microsomes.

Leon Moore, +1 more
- 01 Apr 1978 - 
TL;DR: Recent studies on the regulation of microsomal calcium uptake from cells grown in tissue culture concluded that both microsome preparations contain a “relaxing factor” that prevents contraction, which is an important regulatory ion in the control of both motility and growth of cells in tissueculture.
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Studies on an ACTH-activated adenyl cyclase from a mouse adrenal tumor

Ira Pastan, +2 more
- 01 Oct 1970 - 
TL;DR: Adenyl cyclase from an ACTH sensitive adrenal tumor has been reduced to a molecular weight of 3 to 7 million by treatment of a lyophilized preparation of the particulate enzyme in a French pressure cell, a Nossal shaker or by sonication in the presence of both a phospholipid and fluoride.
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Recombinant Immunotoxins: From Basic Research to Cancer Therapy

Ulrich Brinkmann, +1 more
- 01 Oct 1995 - 
TL;DR: This review describes immunotoxins, molecules that contain an antibody-derived antigen binding region (Fv) coupled to a bacterial toxin, most commonly Diphtheria toxin or Pseudomonas exotoxin.
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GDEP, a new gene differentially expressed in normal prostate and prostate cancer.

Pär Olsson, +7 more
- 01 Sep 2001 - 
TL;DR: The database of human expressed sequence tags (dbEST) is a potential source for the identification of tissue specific genes from cDNA libraries from different tissues cell types and tumors.