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Ira Pastan
Researcher at Laboratory of Molecular Biology
Publications - 1304
Citations - 113191
Ira Pastan is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Immunotoxin & Pseudomonas exotoxin. The author has an hindex of 160, co-authored 1286 publications receiving 110069 citations. Previous affiliations of Ira Pastan include Heidelberg University & National Institutes of Health.
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Primate antibody response to immunotoxin: serological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin.
TL;DR: A computer-aided analysis was done to predict the immunologically relevant areas of PE38 and showed that the predicted areas of immunogenicity agree with the reactivity of the anti-PE38 antibodies to peptides and to the mutants of PE.
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Identification of Three New Alternate Human Kallikrein 2 Transcripts: Evidence of Long Transcript and Alternative Splicing
TL;DR: The identification of long hKLK2 transcript and an alternative spliced form of the hKlK2 gene indicates that regulation of the gene is complex.
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Insulin stimulation of amino acid transport in isolated rat hepatocytes is independent of hormone internalization
TL;DR: The data indicate that the internalization of insulin is not required for the expression of its biological effect on amino acid transport and that methylamine did not decrease the binding capacity of the cells.
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Pyridine nucleotides in the thyroid. ii. the effect of thyroid-stimulating hormone, epinephrine, serotonin, acetylcholine, menadione, and glucose concentration on the levels ot tpn and tpnh.
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Recognition of Mesothelin by the Therapeutic Antibody MORAb-009 STRUCTURAL AND MECHANISTIC INSIGHTS
TL;DR: It is shown here that MORAb-009 recognizes a non-linear epitope that is contained in the first 64-residue fragment of the mesothelin, and it is demonstrated that the recognition is independent of glycosylation state of the protein but sensitive to the loss of a disulfide bond linking residues Cys-7 andCys-31.