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Jan Reedijk

Researcher at Leiden University

Publications -  1165
Citations -  45902

Jan Reedijk is an academic researcher from Leiden University. The author has contributed to research in topics: Ligand & Crystal structure. The author has an hindex of 80, co-authored 1163 publications receiving 43747 citations. Previous affiliations of Jan Reedijk include Nagoya City University & University of Münster.

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Synthesis, structure, and spectroscopic properties of copper(II) compounds containing nitrogen–sulphur donor ligands; the crystal and molecular structure of aqua[1,7-bis(N-methylbenzimidazol-2′-yl)-2,6-dithiaheptane]copper(II) perchlorate

TL;DR: In this article, the linear quadridentate N2S2 donor ligand 1,7-bis(N-methylbenzimidazol-2′-yl)-2,6-dithiaheptane (bmdhp) forms mono-and di-hydrate 1 : 1 copper(II) complexes which are significantly more stable toward autoreduction than those of the non-methylated analogue.
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Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation

TL;DR: In kinetic studies on the formation of the various adducts, a clear preference of the Pt compound to react with guanines occurring in the base sequence d(pGpG) was established and the method was used to optimize the digestion conditions for cis-DDP-treated DNA.
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New clues for platinum antitumor chemistry: Kinetically controlled metal binding to DNA

TL;DR: The kinetics of ligand exchange around platinum appear to play a crucial role, and the possible role of other ligands as intermediates, especially those with S-donor sites, is of great interest.