L
Lewis L. Lanier
Researcher at University of California, San Francisco
Publications - 576
Citations - 93495
Lewis L. Lanier is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Interleukin 21 & Natural killer cell. The author has an hindex of 159, co-authored 554 publications receiving 86677 citations. Previous affiliations of Lewis L. Lanier include University of Rome Tor Vergata & Cancer Research Institute.
Papers
More filters
Journal ArticleDOI
New nomenclature for MHC receptors.
Journal ArticleDOI
Shades of grey — the blurring view of innate and adaptive immunity
TL;DR: This special issue of Nature Reviews Immunology focuses on the types of lymphocyte that blur the traditional boundaries between the innate and adaptive immune systems.
Journal ArticleDOI
Membrane anchoring of a human IgG Fc receptor (CD16) determined by a single amino acid.
TL;DR: The primary structural requirements for PI-linkage were examined by constructing a series of hybrid cDNA molecules that encode membrane glycoproteins anchored by phosphatidylinositol (PI)-glycan and transmembrane polypeptides, respectively.
Journal ArticleDOI
NK cell regulation of T cell-mediated responses.
Alessandra Zingoni,Alessandra Zingoni,Thierry Sornasse,Benjamin G. Cocks,Yuetsu Tanaka,Angela Santoni,Lewis L. Lanier +6 more
TL;DR: Evidence is provided that activated human NK cells are able of promoting TcR-dependent proliferation of resting autologous peripheral blood CD4(+) T cells by a process that involves costimulatory molecules of the immunoglobulin (Ig) and tumor necrosis factor (TNF) superfamilies, suggesting a novel link between natural and adaptative immune responses.
Journal ArticleDOI
DAP12: an adapter protein with dual functionality.
TL;DR: Evidence is presented that DAP12 can suppress as well as activate NK cells and that this ability to inhibit myeloid functions is also demonstrated.