L
Lewis L. Lanier
Researcher at University of California, San Francisco
Publications - 576
Citations - 93495
Lewis L. Lanier is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Interleukin 21 & Natural killer cell. The author has an hindex of 159, co-authored 554 publications receiving 86677 citations. Previous affiliations of Lewis L. Lanier include University of Rome Tor Vergata & Cancer Research Institute.
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Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes
Kavitha Narayan,Katelyn E Sylvia,Nidhi Malhotra,Catherine C. Yin,Gregory W. Martens,Therese Vallerskog,Hardy Kornfeld,Na Xiong,Nadia R Cohen,Michael B. Brenner,Leslie J. Berg,Joonsoo Kang,Yan Zhou,Susan A. Shinton,Richard R. Hardy,Natalie A. Bezman,Joseph C. Sun,Charles C. Kim,Lewis L. Lanier,Jennifer Miller,Brian D. Brown,Miriam Merad,Anne L. Fletcher,Kutlu G. Elpek,Angelique Bellemare-Pelletier,Deepali Malhotra,Shannon J. Turley,Katelyn Sylvia,Roi Gazit,Brian S. Garrison,Derrick J. Rossi,Vladimir Jojic,Daphne Koller,Radu Jianu,David H. Laidlaw,James C. Costello,James J. Collins,Nadia Cohen,Patrick J. Brennan,Michael Brenner,Tal Shay,Aviv Regev,Francis Kim,Tata Nageswara Rao,Amy J. Wagers,Emmanuel L. Gautier,Claudia Jakubzick,Gwendalyn J. Randolph,Paul A. Monach,Adam J Best,Jamie Knell,Ananda W. Goldrath,Tracy Heng,Taras Kreslavsky,Michio W. Painter,Diane Mathis,Christophe Benoist +56 more
Journal Article
Lectin-dependent and anti-CD3 induced cytotoxicity are preferentially mediated by peripheral blood cytotoxic T lymphocytes expressing Leu-7 antigen.
TL;DR: The finding that NK cell-mediated cytotoxicity was unaffected by these lectins refutes the hypothesis that lectin-dependent cellular cytot toxicity is simply a result of effector and target agglutination and represents a population of in vivo primed CTL possibly against viral antigens.
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Evidence for three types of human cytotoxic lymphocyte
TL;DR: It is argued that functional criteria do not adequately distinguish types of cytotoxic cell, and a classification based on recognition structure is proposed, which identifies three distinct effector cells.
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Natural killer cells remember: an evolutionary bridge between innate and adaptive immunity?
Joseph C. Sun,Lewis L. Lanier +1 more
TL;DR: New findings showing how NK cells possess nearly all of the features of adaptive immunity including memory are proposed, proposing the placement of NK cells as an “evolutionary bridge” between innate and adaptive immunity.
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The cytomegalovirus m155 gene product subverts natural killer cell antiviral protection by disruption of H60-NKG2D interactions.
Melissa B. Lodoen,Gerardo Abenes,Sean Umamoto,Jeffrey P. Houchins,Fenyong Liu,Lewis L. Lanier +5 more
TL;DR: Down-regulation of H60 by m155 is a powerful mechanism of inhibiting NKG2D-mediated antiviral function.