Mario Fasold

TL;DR: The complete SEQC data sets, comprising >100 billion reads, provide unique resources for evaluating RNA-seq analyses for clinical and regulatory settings, and measurement performance depends on the platform and data analysis pipeline, and variation is large for transcript-level profiling.

TL;DR: In this article, the authors sequenced the genome of spotted gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome duplication (TGD).

TL;DR: A proposed standard 'dashboard' of metrics derived from analysis of external spike-in RNA control ratio mixtures enable assessment of diagnostic performance of differentially expressed transcript lists, limit of detection of ratio (LODR) estimates and expression ratio variability and measurement bias.

TL;DR: DARIO, a free web service that allows to study short read data from small RNA-seq experiments, provides a wide range of analysis features, including quality control, read normalization, ncRNA quantification and prediction of putative nc RNA candidates.

TL;DR: It is concluded that lncRNA genes are evolutionary ancient components of vertebrate genomes that show an unexpected and unprecedented evolutionary plasticity.