M
Mark E. Cooper
Researcher at University of Queensland
Publications - 1514
Citations - 141899
Mark E. Cooper is an academic researcher from University of Queensland. The author has contributed to research in topics: Diabetes mellitus & Diabetic nephropathy. The author has an hindex of 158, co-authored 1463 publications receiving 124887 citations. Previous affiliations of Mark E. Cooper include University of Cambridge & University of Adelaide.
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Journal ArticleDOI
Preventing diabetes in patients with hypertension: one more reason to block the renin-angiotensin system.
TL;DR: The findings of several recent clinical trials have suggested that blockade of the renin–angiotensin system (RAS) may protect against the development of de-novo diabetes in ‘at risk’ patients, and it is hoped that these studies will demonstrate the true potential of blockade ofThe RAS for the prevention of diabetes.
Journal ArticleDOI
Compression force sensing regulates integrin αIIbβ3 adhesive function on diabetic platelets.
Lining Ju,James D. McFadyen,Saheb Al-Daher,Imala Alwis,Imala Alwis,Imala Alwis,Yunfeng Chen,Lotte Lindhardt Tonnesen,Lotte Lindhardt Tonnesen,Lotte Lindhardt Tonnesen,Sophie Maiocchi,Sophie Maiocchi,Brianna Coulter,Brianna Coulter,Anna C. Calkin,Anna C. Calkin,Eric I. Felner,Neale Cohen,Yuping Yuan,Yuping Yuan,Yuping Yuan,Simone M. Schoenwaelder,Simone M. Schoenwaelder,Simone M. Schoenwaelder,Mark E. Cooper,Cheng Zhu,Cheng Zhu,Cheng Zhu,Shaun P. Jackson +28 more
TL;DR: It is demonstrated that compressive force activates integrin αIIbβ3 on discoid diabetic platelets and that platelet aggregates can be eliminated by PI 3-kinase inhibition, but not by anti-thrombotics aspirin or clopidogrel.
Book ChapterDOI
Linking biophysical and genetic models to integrate physiology, molecular biology and plant breeding
Journal ArticleDOI
Genotype-by-environment interactions for grain yield associated with water availability at flowering in rainfed lowland rice
Makara Ouk,J. Basnayake,Mitsuru Tsubo,Shu Fukai,Krista Fischer,S. Kang,S. Men,V. Thun,Mark E. Cooper +8 more
TL;DR: A major factor contributing to the large G x L x Y interactions for GY was late maturing genotypes being affected greatly when soil water availability at flowering was reduced greatly, compared to earlier maturingGenotypes were selected for their high yield and wide adaptation in the rainfed lowlands.