M
Mark E. Cooper
Researcher at University of Queensland
Publications - 1514
Citations - 141899
Mark E. Cooper is an academic researcher from University of Queensland. The author has contributed to research in topics: Diabetes mellitus & Diabetic nephropathy. The author has an hindex of 158, co-authored 1463 publications receiving 124887 citations. Previous affiliations of Mark E. Cooper include University of Cambridge & University of Adelaide.
Papers
More filters
Journal ArticleDOI
Linagliptin Lowers Albuminuria on Top of Recommended Standard Treatment in Patients With Type 2 Diabetes and Renal Dysfunction
Per-Henrik Groop,Per-Henrik Groop,Mark E. Cooper,Vlado Perkovic,Angela Emser,Hans-Juergen Woerle,Maximilian von Eynatten +6 more
TL;DR: Linagliptin administered in addition to stable RAAS inhibitors led to a significant reduction in albuminuria in patients with type 2 diabetes and renal dysfunction, independent of changes in glucose level or SBP.
Journal ArticleDOI
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.
Paul J. Baker,Paul J. Baker,Dave Boucher,Damien Bierschenk,Christina Tebartz,Paul G. Whitney,Damian B D'Silva,Damian B D'Silva,Maria C. Tanzer,Maria C. Tanzer,Mercedes Monteleone,Avril A. B. Robertson,Mark E. Cooper,Silvia Alvarez-Diaz,Silvia Alvarez-Diaz,Marco J Herold,Marco J Herold,Sammy Bedoui,Kate Schroder,Seth L. Masters,Seth L. Masters +20 more
TL;DR: The results identify the NLRP3 inflammasome as the specific platform for IL‐1β maturation, downstream of cytoplasmic LPS detection by caspase‐4/5, and show that both caspases are functionally important for appropriate responses to intracellular Gram‐negative bacteria.
Journal ArticleDOI
Lowering Blood Pressure Reduces Renal Events in Type 2 Diabetes
Bastiaan E. de Galan,Bastiaan E. de Galan,Vlado Perkovic,Toshiharu Ninomiya,Avinesh Pillai,Anushka Patel,Alan Cass,Bruce Neal,Neil R Poulter,Stephen B. Harrap,Carl Erik Mogensen,Mark E. Cooper,Michel Marre,Bryan Williams,Pavel Hamet,Giuseppe Mancia,Mark Woodward,Paul Glasziou,Diederick E. Grobbee,Stephen MacMahon,John Chalmers +20 more
TL;DR: BP-lowering treatment with perindopril-indapamide administered routinely to individuals with type 2 diabetes provides important renoprotection, even among those with initial BP <120/70 mmHg, and a BP threshold below which renal benefit is lost is not identified.
Journal ArticleDOI
The relationship between shell size and Mg/Ca, Sr/Ca, δ18O, and δ13C of species of planktonic foraminifera
TL;DR: The relationship between shell size and Mg/Ca, Sr/Ca and?13C of planktonic foraminiferal calcite has been investigated using seventeen species in six different size fractions as discussed by the authors.
Journal ArticleDOI
Environment characterization as an aid to wheat improvement: interpreting genotype–environment interactions by modelling water-deficit patterns in North-Eastern Australia
TL;DR: A modelling approach is proposed here to characterize broadly (large geographic area, long-term period) and locally (field experiment) drought-related environmental stresses, which enables breeders to analyse their experimental trials with regard to the broad population of environments that they target.