M
Mark E. Cooper
Researcher at University of Queensland
Publications - 1514
Citations - 141899
Mark E. Cooper is an academic researcher from University of Queensland. The author has contributed to research in topics: Diabetes mellitus & Diabetic nephropathy. The author has an hindex of 158, co-authored 1463 publications receiving 124887 citations. Previous affiliations of Mark E. Cooper include University of Cambridge & University of Adelaide.
Papers
More filters
Journal ArticleDOI
Attenuation of diabetes-associated mesenteric vascular hypertrophy with perindopril: morphological and molecular biological studies.
Mark E. Cooper,Zemin Cao,Jonathan R. Rumble,Karin Jandeleit,Terri J. Allen,Richard E. Gilbert +5 more
TL;DR: ACE inhibition attenuates many of the vascular changes observed in experimental diabetes and may have important clinical implications as a vasoprotective agent in human diabetes.
Journal ArticleDOI
Novel hexad repeats conserved in a putative transporter with restricted expression in cell types associated with growth, calcium exchange and homeostasis
Geoffrey Brasier,Christos Tikellis,Loredanna Xuereb,Jillian Craigie,David J. Casley,Christopher S. Kovacs,Neva J. Fudge,Renate Kalnins,Mark E. Cooper,Peter J. Wookey +9 more
TL;DR: It is proposed that the transporter is specific for a calcium-chelator complex and is important for growth and calcium metabolism and was consistent with a role in calcium homeostasis in the fetus and in developing mouse kidney.
Journal ArticleDOI
Empagliflozin modulates renal sympathetic and heart rate baroreflexes in a rabbit model of diabetes.
Cindy Gueguen,Sandra L. Burke,Benjamin Barzel,Nina Eikelis,Anna M. D. Watson,Jay C. Jha,Kristy L. Jackson,Yusuke Sata,Yusuke Sata,Kyungjoon Lim,Kyungjoon Lim,Gavin W. Lambert,Karin Jandeleit-Dahm,Karin Jandeleit-Dahm,Mark E. Cooper,Mark E. Cooper,Merlin C. Thomas,Geoffrey A. Head,Geoffrey A. Head +18 more
TL;DR: As empagliflozin can restore diabetes-induced augmented sympathetic reflexes, this may be beneficial in diabetic patients and a similar action of the diuretic acetazolamide suggests that the mechanism may involve increased sodium and water excretion.
Journal ArticleDOI
Clinical and demographic risk factors associated with mortality during early adulthood in a population‐based cohort of childhood‐onset Type 1 diabetes
Mark E. Cooper,Mark E. Cooper,N H de Klerk,Timothy W. Jones,Timothy W. Jones,Elizabeth A. Davis,Elizabeth A. Davis +6 more
TL;DR: To calculate standardized mortality ratios and to assess the association between paediatric clinical factors and higher risk of mortality during early adulthood in a population‐based cohort of subjects with Type 1 diabetes, a data collection and analysis is conducted.
Journal ArticleDOI
Increased tubular organic ion clearance following chronic ACE inhibition in patients with type 1 diabetes
Merlin C. Thomas,George Jerums,Con Tsalamandris,Richard J MacIsaac,Sianna Panagiotopoulos,Mark E. Cooper +5 more
TL;DR: Organic ion clearance is increased in patients with diabetes following chronic ACE inhibition, consistent with experimental models showing increased ion transporter expression and improved tubular blood flow, following blockade of the renin-angiotensin system (RAS).