Mark E. Cooper

TL;DR: In this article, the results of a multi-proxy study to reconstruct surface water pCO2 concentrations in the northern Arabian Sea were reported, showing that this area of the oceans has been a constant source of CO2 to the atmosphere during the interval 5-29 ka, and that the intensity of this source was greatest between 11 and 17 ka, when atmospheric CO2 levels were rising rapidly.

TL;DR: Long-term studies are needed to determine whether a decrease in albuminuria induced by CEI or CCB in patients with incipient diabetic nephropathy delays or reduces the subsequent rate of decline in glomerular filtration rate and renal structural changes.

TL;DR: In this article, a sulfonyl ureas and related compounds are used in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.

TL;DR: A role for CTR in the activation of some premigratory neuroblasts in the CNS is indicated as well as a possible role later in an undefined function associated with mature neurons of particular nuclei.

TL;DR: This review discusses successful strategies and potential pitfalls to assembling a natural product-based library suitable for high-throughput screening and the logistics of moving from an assay hit to pure bioactive compound are discussed.