Mark E. Cooper

TL;DR: In this article, the authors investigated how well-irrigated (low-stress) nursery environments predict yield of lines in target environments that varied in degree of water limitation and found that yield under low-stress nursery conditions was an effective predictor of yield under similar low-stressed target environments (r = 0.89, P 0.05; severe stress r = -0.08, P > 0.

TL;DR: First estimates of potential excess mortality among people with cancer and multimorbidity due to the COVID-19 emergency are provided and there is an urgent need for weekly data on cause-specific excess mortality, cancer diagnosis and treatment provision and better intelligence on the use of effective treatments for comorbidities.

TL;DR: Following renal mass reduction there is pathological tubular expression of various components of the RAS, and tubular renin expression was reduced with ACE inhibition, indicating changes within the intrarenal RAS may be pathogenetically linked to the development of tubulointerstitial injury.

TL;DR: The failure of either antioxidants or aldose reductase inhibition to reproduce the renal effects of aminoguanidine suggest that aminogsuanidine may act predominantly via inhibition of advanced glycation and not via the alternative biochemical processes evaluated in this study.

TL;DR: The beneficial effects of blockade of either pathway underline the importance of this interaction in diabetic renal disease and the aging kidney.