S
Sahr M. Gevao
Researcher at University of Sierra Leone
Publications - 14
Citations - 2090
Sahr M. Gevao is an academic researcher from University of Sierra Leone. The author has contributed to research in topics: Ebola virus & Sierra leone. The author has an hindex of 10, co-authored 14 publications receiving 1824 citations.
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Journal ArticleDOI
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
Stephen K. Gire,Stephen K. Gire,Augustine Goba,Kristian G. Andersen,Kristian G. Andersen,Rachel Sealfon,Rachel Sealfon,Daniel J. Park,Lansana Kanneh,Simbirie Jalloh,Mambu Momoh,Mohamed Fullah,Gytis Dudas,Shirlee Wohl,Shirlee Wohl,Lina M. Moses,Nathan L. Yozwiak,Nathan L. Yozwiak,Sarah M. Winnicki,Sarah M. Winnicki,Christian B. Matranga,Christine M. Malboeuf,James Qu,Adrianne Gladden,Stephen F. Schaffner,Stephen F. Schaffner,Xiao Yang,Pan Pan Jiang,Pan Pan Jiang,Mahan Nekoui,Mahan Nekoui,Andrés Colubri,Moinya Ruth Coomber,Mbalu Fonnie,Alex Moigboi,Michael Gbakie,Fatima K. Kamara,Veronica Tucker,Edwin Konuwa,Sidiki Saffa,Josephine Sellu,Abdul A. Jalloh,Alice Kovoma,James Koninga,Ibrahim Mustapha,Kandeh Kargbo,Momoh Foday,Mohamed Yillah,Franklyn Kanneh,Willie Robert,James L.B. Massally,Sinéad B. Chapman,James Bochicchio,Cheryl I. Murphy,Chad Nusbaum,Sarah Young,Bruce W. Birren,Donald S. Grant,John S. Scheiffelin,Eric S. Lander,Eric S. Lander,Eric S. Lander,Christian T. Happi,Sahr M. Gevao,Andreas Gnirke,Andrew Rambaut,Andrew Rambaut,Robert F. Garry,S. Humarr Khan,Pardis C. Sabeti,Pardis C. Sabeti +70 more
TL;DR: This West African variant likely diverged from central African lineages around 2004, crossed from Guinea to Sierra Leone in May 2014, and has exhibited sustained human-to-human transmission subsequently, with no evidence of additional zoonotic sources.
Journal ArticleDOI
Virus genomes reveal factors that spread and sustained the Ebola epidemic
Gytis Dudas,Gytis Dudas,Luiz Max Carvalho,Trevor Bedford,Andrew J. Tatem,Guy Baele,Nuno R. Faria,Daniel J. Park,Jason T. Ladner,Armando Arias,Armando Arias,Danny Asogun,Filip Bielejec,Sarah L Caddy,Matthew Cotten,Matthew Cotten,Jonathan D'ambrozio,Simon Dellicour,Antonino Di Caro,Joseph W. Diclaro,Sophie Duraffour,Michael J. Elmore,Lawrence Fakoli,Ousmane Faye,Merle L. Gilbert,Sahr M. Gevao,Stephen K. Gire,Stephen K. Gire,Adrianne Gladden-Young,Andreas Gnirke,Augustine Goba,Donald S. Grant,Bart L. Haagmans,Julian A. Hiscox,Umaru Jah,Jeffrey R. Kugelman,Di Liu,Jia Lu,Christine M. Malboeuf,Suzanne Mate,David A. Matthews,Christian B. Matranga,Luke W. Meredith,Luke W. Meredith,James Qu,Joshua Quick,Susan D. Pas,My V. T. Phan,My V. T. Phan,Georgios Pollakis,Chantal B.E.M. Reusken,Mariano Sanchez-Lockhart,Stephen F. Schaffner,John S. Schieffelin,Rachel Sealfon,Rachel Sealfon,Etienne Simon-Loriere,Etienne Simon-Loriere,Saskia L. Smits,Kilian Stoecker,Lucy Thorne,Ekaete Alice Tobin,Mohamed A. Vandi,Simon J. Watson,Kendra West,Shannon L.M. Whitmer,Michael R. Wiley,Sarah M. Winnicki,Sarah M. Winnicki,Shirlee Wohl,Shirlee Wohl,Roman Wölfel,Nathan L. Yozwiak,Nathan L. Yozwiak,Kristian G. Andersen,Kristian G. Andersen,Sylvia O. Blyden,Fatorma K. Bolay,Miles W. Carroll,Bernice Dahn,Boubacar Diallo,Pierre Formenty,Christophe Fraser,George F. Gao,Robert F. Garry,Ian Goodfellow,Ian Goodfellow,Stephan Günther,Christian T. Happi,Edward C. Holmes,Brima Kargbo,Sakoba Keita,Paul Kellam,Paul Kellam,Marion Koopmans,Jens H. Kuhn,Nicholas J. Loman,N’Faly Magassouba,Dhamari Naidoo,Stuart T. Nichol,Tolbert Nyenswah,Gustavo Palacios,Oliver G. Pybus,Pardis C. Sabeti,Pardis C. Sabeti,Amadou A. Sall,Ute Ströher,Isatta Wurie,Marc A. Suchard,Philippe Lemey,Andrew Rambaut +110 more
TL;DR: It is revealed that this large epidemic was a heterogeneous and spatially dissociated collection of transmission clusters of varying size, duration and connectivity, which will help to inform interventions in future epidemics.
Journal ArticleDOI
Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone
Daniel J. Park,Gytis Dudas,Shirlee Wohl,Shirlee Wohl,Augustine Goba,Shannon L.M. Whitmer,Kristian G. Andersen,Rachel Sealfon,Rachel Sealfon,Jason T. Ladner,Jeffrey R. Kugelman,Christian B. Matranga,Sarah M. Winnicki,Sarah M. Winnicki,James Qu,Stephen K. Gire,Stephen K. Gire,Adrianne Gladden-Young,Simbirie Jalloh,Dolo Nosamiefan,Nathan L. Yozwiak,Nathan L. Yozwiak,Lina M. Moses,Pan Pan Jiang,Pan Pan Jiang,Aaron E. Lin,Aaron E. Lin,Stephen F. Schaffner,Stephen F. Schaffner,Brian H. Bird,Jonathan S. Towner,Mambu Mamoh,Michael Gbakie,Lansana Kanneh,David Kargbo,James L.B. Massally,Fatima K. Kamara,Edwin Konuwa,Josephine Sellu,Abdul A. Jalloh,Ibrahim Mustapha,Momoh Foday,Mohamed Yillah,Bobbie R. Erickson,Tara K. Sealy,Dianna M. Blau,Christopher D. Paddock,Aaron C. Brault,Brian R. Amman,Jane Basile,Scott W. Bearden,Jessica A. Belser,Eric Bergeron,Shelley Campbell,Ayan K. Chakrabarti,Kimberly A. Dodd,Mike Flint,Aridth Gibbons,Christin H. Goodman,John D. Klena,Laura K. Mcmullan,Laura Morgan,Brandy J. Russell,Johanna S. Salzer,Angela J. Sanchez,David Wang,Irwin Jungreis,Christopher Tomkins-Tinch,Andrey Kislyuk,Michael F. Lin,Sinéad B. Chapman,Bronwyn MacInnis,Ashley Matthews,Ashley Matthews,James Bochicchio,Lisa E. Hensley,Jens H. Kuhn,Chad Nusbaum,John S. Schieffelin,Bruce W. Birren,Marc Forget,Stuart T. Nichol,Gustavo Palacios,Daouda Ndiaye,Christian T. Happi,Sahr M. Gevao,Mohamed A. Vandi,Brima Kargbo,Edward C. Holmes,Trevor Bedford,Andreas Gnirke,Ute Ströher,Andrew Rambaut,Andrew Rambaut,Robert F. Garry,Pardis C. Sabeti,Pardis C. Sabeti +96 more
TL;DR: Analysis of sequences from 232 patients sampled over 7 months in Sierra Leone, along with 86 previously released genomes from earlier in the epidemic, confirms sustained human-to-human transmission within Sierra Leone and finds no evidence for import or export of EBOV across national borders after its initial introduction.
Journal ArticleDOI
Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits
James E. Robinson,Kathryn M. Hastie,Robert W. Cross,Rachael E. Yenni,Deborah H. Elliott,Julie A. Rouelle,Chandrika B. Kannadka,Ashley A. Smira,Courtney E Garry,Benjamin T. Bradley,Haini Yu,Jeffrey G. Shaffer,Matthew L. Boisen,Jessica N. Hartnett,Michelle Zandonatti,Megan M. Rowland,Megan L. Heinrich,Luis Martinez-Sobrido,Benson Yee Hin Cheng,Juan Carlos de la Torre,Kristian G. Andersen,Augustine Goba,Mambu Momoh,Mohamed Fullah,Michael Gbakie,Lansana Kanneh,Veronica J. Koroma,Richard Fonnie,Simbirie Jalloh,Brima Kargbo,Mohamed A. Vandi,Momoh Gbetuwa,Odia Ikponmwosa,Danny Asogun,Peter O Okokhere,Onikepe A. Follarin,Onikepe A. Follarin,John S. Schieffelin,Kelly R. Pitts,Joan B. Geisbert,Peter C. Kulakoski,Russell B. Wilson,Christian T. Happi,Christian T. Happi,Pardis C. Sabeti,Pardis C. Sabeti,Sahr M. Gevao,S. Humarr Khan,Donald S. Grant,Thomas W. Geisbert,Erica Ollmann Saphire,Luis M. Branco,Robert F. Garry +52 more
TL;DR: Cloned 113 human monoclonal antibodies specific for LASV glycoproteins from memory B cells of Lassa fever survivors from West Africa guide strategies for immunotherapeutic development and vaccine design.
Journal ArticleDOI
Analytical Validation of the ReEBOV Antigen Rapid Test for Point-of-Care Diagnosis of Ebola Virus Infection.
Robert W. Cross,Matthew L. Boisen,Molly M. Millett,Diana K. S. Nelson,Darin Oottamasathien,Jessica N. Hartnett,Abigal B. Jones,Augustine Goba,Mambu Momoh,Mohamed Fullah,Zachary A. Bornholdt,Marnie L. Fusco,Dafna M. Abelson,Shun-ichiro Oda,Bethany L. Brown,Ha Pham,Megan M. Rowland,Krystle N. Agans,Joan B. Geisbert,Megan L. Heinrich,Peter C. Kulakosky,Jeffrey G. Shaffer,John S. Schieffelin,Brima Kargbo,Momoh Gbetuwa,Sahr M. Gevao,Russell B. Wilson,Erica Ollmann Saphire,Kelly R. Pitts,Sheik Humarr Khan,Donald S. Grant,Thomas W. Geisbert,Luis M. Branco,Robert F. Garry +33 more
TL;DR: The analytical validation presented here contributed to the ReEBOV RDT being the first antigen-based assay to receive FDA and World Health Organization emergency use authorization for this EVD outbreak, in February 2015.