T
Trevor W. Robbins
Researcher at University of Cambridge
Publications - 1184
Citations - 177352
Trevor W. Robbins is an academic researcher from University of Cambridge. The author has contributed to research in topics: Prefrontal cortex & Cognition. The author has an hindex of 231, co-authored 1137 publications receiving 164437 citations. Previous affiliations of Trevor W. Robbins include Centre national de la recherche scientifique & Massachusetts Institute of Technology.
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Journal ArticleDOI
Selective Remediation of Reversal Learning Deficits in the Neurodevelopmental MAM Model of Schizophrenia by a Novel mGlu5 Positive Allosteric Modulator
Francois Gastambide,Marie-Caroline Cotel,Gary Gilmour,Michael J. O'Neill,Trevor W. Robbins,Mark D. Tricklebank +5 more
TL;DR: Findings confirm that the positive modulation of mGlu5 receptors may have beneficial effects in the treatment of certain aspects of cognitive impairment associated with schizophrenia and illustrates the importance of studying putative cognitive enhancing drug effects in a number of models which may have implications for the future development of the compound.
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Decision-making deficits in drug addiction.
Luke Clark,Trevor W. Robbins +1 more
TL;DR: Using recording of autonomic function during performance of two gambling tasks, Bechara et al. have recently identified three distinct neuropsychological subtypes in individuals with substance dependence that reflect dissociable patterns of disruption in limbic brain circuitry.
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Spatial Working Memory Deficits in Schizophrenia: Relationship With Tardive Dyskinesia and Negative Symptoms
TL;DR: In schizophrenia, orofacial tardive dyskinesia and evident negative symptoms are relatively independent markers of compromise of the cerebral systems that mediate spatial working memory.
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Differential Contributions of Dopamine and Serotonin to Orbitofrontal Cortex Function in the Marmoset
TL;DR: Monkeys with serotonin depletions of the OFC displayed stimulus-bound responding on both tests of conditioned reinforcement and discrimination extinction suggesting that orbitofrontal serotonin plays a specific role in preventing competing, task irrelevant, salient stimuli from biasing responding.
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Serotonin modulates the effects of Pavlovian aversive predictions on response vigor.
Molly J. Crockett,Luke Clark,Annemieke M. Apergis-Schoute,Sharon Morein-Zamir,Trevor W. Robbins +4 more
TL;DR: Tryptophan depletion removed the bias against responding on the punished button, and abolished slowing in the presence of punished stimuli, irrespective of response, suggesting additional specificity for the influence of 5-HT on aversively motivated behavioral inhibition.