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Trevor W. Robbins

Researcher at University of Cambridge

Publications -  1184
Citations -  177352

Trevor W. Robbins is an academic researcher from University of Cambridge. The author has contributed to research in topics: Prefrontal cortex & Cognition. The author has an hindex of 231, co-authored 1137 publications receiving 164437 citations. Previous affiliations of Trevor W. Robbins include Centre national de la recherche scientifique & Massachusetts Institute of Technology.

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Chronic cocaine but not chronic amphetamine use is associated with perseverative responding in humans

TL;DR: Findings provide convincing evidence for response perseveration in cocaine users during probabilistic reversal-learning, and Pharmacological differences between amphetamine and cocaine, in particular their respective effects on the 5-HT system, may account for the divergent task performance between the two psychostimulant user groups.
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Dissociating Inhibition, Attention, and Response Control in the Frontoparietal Network Using Functional Magnetic Resonance Imaging

TL;DR: The results are consistent with the hypothesis that this region plays a key role in the integration of bottom-up, sensory information with top-down, response-related information to facilitate flexible, goal-directed behavior.
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Increased acetylcholine release in the rat medial prefrontal cortex during performance of a visual attentional task.

TL;DR: It is shown that ACh efflux in the rat mPFC is increased during performance of a 5‐CSRTT, but has found no evidence to support a specific relationship between cholinergic cortical output and attentional performance.
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High impulsivity predicts relapse to cocaine-seeking after punishment-induced abstinence.

TL;DR: In a preliminary study, it is found that the selective noradrenaline reuptake inhibitor, atomoxetine, a drug known to reduce impulsivity, prevented the reinstatement of cocaine-seeking.
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Intra-prefrontal 8-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats.

TL;DR: Results indicate that modulation of 5-HT function within the mPFC via distinct receptors can enhance performance on the 5CSRT, and suggest a mechanism by which serotonergic agents improve cognitive function.