T
Trevor W. Robbins
Researcher at University of Cambridge
Publications - 1184
Citations - 177352
Trevor W. Robbins is an academic researcher from University of Cambridge. The author has contributed to research in topics: Prefrontal cortex & Cognition. The author has an hindex of 231, co-authored 1137 publications receiving 164437 citations. Previous affiliations of Trevor W. Robbins include Centre national de la recherche scientifique & Massachusetts Institute of Technology.
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Journal ArticleDOI
Distribution and some projections of cholinergic neurons in the brain of the common marmoset, Callithrix jacchus.
TL;DR: The combination of the retrograde transport of HRP‐WGA with ChAT immunohistochemistry revealed the distribution of neurons in the Ch4 cell group projecting to the dorsolateral prefrontal cortex, which suggests some degree of topographical organization of Ch4 projections to the cortical mantle.
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Verbal fluency in Huntington's disease: a longitudinal analysis of phonemic and semantic clustering and switching.
Aileen K Ho,Barbara J. Sahakian,Trevor W. Robbins,Roger A. Barker,Anne Elizabeth Rosser,John R. Hodges +5 more
TL;DR: Phonemic switching alone drove verbal fluency performance and this selective impairment can be explained by the progressive involvement of frontostriatal circuitry in the natural progression of HD.
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Selective deficits in attentional performance on the 5-choice serial reaction time task following pedunculopontine tegmental nucleus lesions.
TL;DR: The results suggest that PPTg lesions produce a global deficit in attention, rather than a specific impairment in one process, which may be through its direct projections to the forebrain cholinergic system or, indirectly, through activation of thalamocortical projections.
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The BDNF Val66Met polymorphism has a gender specific influence on planning ability in Parkinson’s disease
Thomas Foltynie,Simon G. J. Lewis,Terry E. Goldberg,Andrew D. Blackwell,Bhaskar Kolachana,Daniel R. Weinberger,Trevor W. Robbins,Roger A. Barker +7 more
TL;DR: It is speculated that BDNF may interact with dopaminergic transmission and dopamine receptor stimulation in the frontostriatal circuitry, with subsequent consequences on cognition in Parkinson’s disease.
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Innovative solutions to novel drug development in mental health
Thomas R. Insel,Valerie Voon,Jeffrey S. Nye,Verity J. Brown,B.M. Altevogt,Edward T. Bullmore,Guy M. Goodwin,Robert Howard,David J. Kupfer,Gavin Malloch,Hugh M. Marston,David J. Nutt,Trevor W. Robbins,Stephen M. Stahl,Stephen M. Stahl,Mark D. Tricklebank,John Williams,Barbara J. Sahakian +17 more
TL;DR: New approaches to identifying and validating potential drug targets are essential and a novel drug toolbox and innovative private-public partnerships are required to enhance understanding of mental health.