Federal University of São Carlos

About: Federal University of São Carlos is a education organization based out in São Carlos, Brazil. It is known for research contribution in the topics: Population & Microstructure. The organization has 16471 authors who have published 34057 publications receiving 456654 citations. The organization is also known as: UFSCar & Federal University of São Carlos.

Androgenic-Anabolic Steroids Associated With Mechanical Loading Inhibit Matrix Metallopeptidase Activity and Affect the Remodeling of the Achilles Tendon in Rats

Abstract: BackgroundThe indiscriminate use of anabolic-androgenic steroids has been shown to induce pathologic changes in the Achilles tendon in several situations.PurposeTo study tendon remodeling in rats treated with anabolic-androgenic steroids combined with an exercise program.Study DesignControlled laboratory study.MethodsWistar rats were grouped as follows: sedentary (group I), injected with anabolic-androgenic steroids only (group II), trained only (group III), and trained and injected with anabolic-androgenic steroids (group IV). The trained groups performed jumps in water: 4 series of 10 jumps each, with an overload of 50% to 70% of the animal's body weight and a 30-second rest interval between series, for 6 weeks. Anabolic-androgenic steroids (5 mg/kg) were injected subcutaneously. Activity of matrix metallopeptidases, a marker for tendon remodeling, was analyzed in tissue extracts by zymography on gelatin–sodium dodecyl sulfate–polyacrylamide gel electrophoresis.ResultsMorphological analyses of tendons s...

The lanky and the corky: Fire-escape strategies in savanna woody species

Abstract: The authors are grateful to the Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP; process: 2010/01835-0); the Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES; process: 1019-11-2); and the Spanish Government (VIRRA and TREVOL projects, CGL2009-12048/BOS and CGL2012-39938-C02-00) for financial support and the scholarships granted to the authors.

Brittle dynamic fracture of crystalline cubic silicon carbide "3C-SiC… via molecular dynamics simulation

Abstract: Brittle fracture dynamics for three low-index crack surfaces, i.e., (110), (111), and (100), in crystalline cubic silicon carbide (3C-SiC) is studied using molecular dynamics simulation. The results exhibit significant orientation dependence: (110) fracture propagates in a cleavage manner; (111) fracture involves slip in the {111¯} planes; and crack branching is observed in (001) fracture. Calculated critical energy release rates, which characterize fracture toughness, are compared with available experimental and ab initio calculation data.

Structural and electronic analysis of the atomic scale nucleation of Ag on α-Ag2WO4 induced by electron irradiation.

Abstract: In this work, we utilise a combination of theory, computation and experiments to understand the early events related to the nucleation of Ag filaments on α-Ag2WO4 crystals, which is driven by an accelerated electron beam from an electron microscope under high vacuum. The growth process and the chemical composition and elemental distribution in these filaments were analysed in depth at the nanoscale level using TEM, HAADF, EDS and XPS; the structural and electronic aspects were systematically studied in using first-principles electronic structure theory within QTAIM framework. The Ag nucleation and formation on α-Ag2WO4 is a result of the order/disorder effects generated in the crystal by the electron-beam irradiation. Both experimental and theoretical results show that this behavior is associated with structural and electronic changes of the [AgO2] and [AgO4] clusters and, to a minor extent, to the [WO6] cluster; these clusters collectively represent the constituent building blocks of α-Ag2WO4.