Institution
Federal University of São Carlos
Education•São Carlos, Brazil•
About: Federal University of São Carlos is a education organization based out in São Carlos, Brazil. It is known for research contribution in the topics: Population & Microstructure. The organization has 16471 authors who have published 34057 publications receiving 456654 citations. The organization is also known as: UFSCar & Federal University of São Carlos.
Topics: Population, Microstructure, Context (language use), Catalysis, Alloy
Papers published on a yearly basis
Papers
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TL;DR: This contrasting situation as a functional divergence between 45S and 5S ribosomal DNAs may reflect the localisation of these sequences in distinct nuclear compartments, leading them to undergo differentiated evolutionary processes.
Abstract: Fluorescence in situhybridisation (FISH) and double FISH experiments were carried out to ascertain the chromosomal distribution pattern of the 45S and 5S ribosomal (r) DNAs in four populations of the characid fish Astyanax scabripinnis – a group considered to be a species complex for its wide karyotypical and morphological diversity. The results regarding the 45S rDNA agreed with this hypothesis, since these sites showed intra- and inter-populational, numerical and positional variations. However, the data obtained with the 5S rDNA probe revealed a highly conserved chromosomal distribution pattern of these sequences among individuals of each population, as well as among the populations analysed. We consider this contrasting situation as a functional divergence between 45S and 5S ribosomal DNAs, which may reflect the localisation of these sequences in distinct nuclear compartments, leading them to undergo differentiated evolutionary processes.
112 citations
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TL;DR: Astyanax scabripinnis specimens from four distinct populations in Brazil were studied with respect to their karyotype macrostructure, nucleolar organizer regions, and 18S and 5S rRNA genes.
Abstract: Astyanax scabripinnis specimens from four distinct populations in Brazil were studied with respect to their karyotype macrostructure, nucleolar organizer regions, and 18S and 5S rRNA genes. The four populations showed a 2n = 50 chromosomes (3 M + 11 SM + 5 ST + 6 A pairs) and 1–2 B chromosomes. No chromosomal differentiations were observed between sexes. Although a karyotypic diversity has been characterized in this fish group, the populations now analyzed presented the same macrokaryotypic pattern. Chromosome mapping of 5S rDNA showed a total of eight sites located in four distinct chromosomal pairs, with no apparent differences among populations. A comparative study on 18S rDNA locations and Ag-NORs showed some secondary NOR sites that are not usually expressed in karyotypes and a probable differential NOR activity among populations. Correlations between these data, environmental conditions and B chromosomes are discussed.
112 citations
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TL;DR: The identified genes and pathways that play key roles in hepatic metabolic adaptations to oxidative stress such as those involved in antioxidant mechanisms will help develop strategies for selection towards the desired phenotype are potentially identified.
Abstract: Efficiency of feed utilization is important for animal production because it can reduce greenhouse gas emissions and improve industry profitability. However, the genetic basis of feed utilization in livestock remains poorly understood. Recent developments in molecular genetics, such as platforms for genome-wide genotyping and sequencing, provide an opportunity to identify genes and pathways that influence production traits. It is known that transcriptional networks influence feed efficiency-related traits such as growth and energy balance. This study sought to identify differentially expressed genes in animals genetically divergent for Residual Feed Intake (RFI), using RNA sequencing methodology (RNA-seq) to obtain information from genome-wide expression profiles in the liver tissues of Nelore cattle. Differential gene expression analysis between high Residual Feed Intake (HRFI, inefficient) and low Residual Feed Intake (LRFI, efficient) groups was performed to provide insights into the molecular mechanisms that underlie feed efficiency-related traits in beef cattle. A total of 112 annotated genes were identified as being differentially expressed between animals with divergent RFI phenotypes. These genes are involved in ion transport and metal ion binding; act as membrane or transmembrane proteins; and belong to gene clusters that are likely related to the transport and catalysis of molecules through the cell membrane and essential mechanisms of nutrient absorption. Genes with functions in cellular signaling, growth and proliferation, cell death and survival were also differentially expressed. Among the over-represented pathways were drug or xenobiotic metabolism, complement and coagulation cascades, NRF2-mediated oxidative stress, melatonin degradation and glutathione metabolism. Our data provide new insights and perspectives on the genetic basis of feed efficiency in cattle. Some previously identified mechanisms were supported and new pathways controlling feed efficiency in Nelore cattle were discovered. We potentially identified genes and pathways that play key roles in hepatic metabolic adaptations to oxidative stress such as those involved in antioxidant mechanisms. These results improve our understanding of the metabolic mechanisms underlying feed efficiency in beef cattle and will help develop strategies for selection towards the desired phenotype.
112 citations
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TL;DR: In this article, the impact of regulatory heterogeneity on agri-food trade using a gravity analysis that relies on detailed data on non-tariff measures (NTMs) collected by the NTM-Impact project is estimated.
Abstract: We estimate the impact of regulatory heterogeneity on agri-food trade using a gravity analysis that relies on detailed data on non-tariff measures (NTMs) collected by the NTM-Impact project. The data cover a broad range of import requirements for agricultural and food products for the EU and nine of its major trade partners. We find that trade is significantly reduced when importing countries have stricter maximum residue limits (MRLs) for plant products than exporting countries. For most other measures, due to their qualitative nature, we were unable to infer whether the importer has stricter standards relative to the exporter, and we do not find a robust relationship between these measures and trade. Our findings suggest that, at least for some import standards, harmonising regulations will increase trade. We also conclude that tariff reductions remain an effective means to increase trade even when NTMs abound.
112 citations
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TL;DR: In this paper, an in-depth study of the chemical modifications, flow and thermo-oxidative degradation behavior as a function of the exposure time of ground tire rubbers to microwaves is presented.
112 citations
Authors
Showing all 16693 results
Name | H-index | Papers | Citations |
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Akihisa Inoue | 126 | 2652 | 93980 |
Michael R. Hamblin | 117 | 899 | 59533 |
Daniel P. Costa | 89 | 531 | 26309 |
Elson Longo | 86 | 1454 | 40494 |
Ross Arena | 81 | 671 | 39949 |
Tom M. Mitchell | 76 | 315 | 41956 |
José Arana Varela | 76 | 748 | 23005 |
Luiz H. C. Mattoso | 66 | 455 | 17432 |
Steve F. Perry | 66 | 294 | 13842 |
Edson R. Leite | 63 | 535 | 15303 |
Juan Andrés | 60 | 493 | 13499 |
Edward R. T. Tiekink | 60 | 1967 | 21052 |
Alex A. Freitas | 60 | 345 | 14789 |
Mary F. Mahon | 59 | 539 | 14258 |
Osvaldo N. Oliveira | 59 | 614 | 16369 |