Fundación Instituto Leloir

About: Fundación Instituto Leloir is a facility organization based out in Buenos Aires, Argentina. It is known for research contribution in the topics: Dentate gyrus & Neurogenesis. The organization has 702 authors who have published 1052 publications receiving 39299 citations.

Growing Latin American Science

Abstract: How can a country rapidly improve its capacity in Science, Technology, and Innovation? Invest in people, as Latin America is doing For Brazil, supporting this effort through international exchange and increased mobility over the past year will substantially enlarge the nation's corpus of highly qualified scientists and technologists Argentina has increased its number of doctoral fellowships and is concentrating on recruiting back Argentine investigators working abroad to advance its own basic research and industry And in Chile, special programs have been funding fellowships to send students abroad to obtain PhD degrees in science These activities reflect the growing desire of Latin American nations to train an educated workforce in the world's best institutions and foster “globalized” science on the continent Nations understand that they must equip themselves with future leaders of scientific and technological research and innovation to compete economically on the international stage In July 2011, the Brazilian government dramatically addressed this challenge by launching the Ciencia sem Fronteiras (CsF) program, which offers, through 2015, 100,000 scholarships for scientific study and research work abroad The program is jointly administered by federal funding agencies and is partly funded by the private sector This Brazilian Science Without Borders program has attracted the interest of universities across the globe that are eager to receive well-funded undergraduate, graduate, and postgraduate students and thereby establish collaborations with a rapidly developing economy CsF specifically focuses on science, technology, engineering, and mathematics, and funds travel and installation expenses, health insurance, and salary for fellowships ranging from 1 to 4 years in academic or industrial centers The program also provides incentives—start-up funds and fellowships—for out-of-country scientists to move to Brazil, whether in the academic, governmental, or industrial sector, even for brief 2-month periods ![Figure][1] CREDIT: ISTOCKPHOTO By the end of 2012, Brazil will have selected more than 20,000 students and postdoctoral fellows to go abroad to 30 different nations in Europe, Asia, Australia, Africa, Central America, and North America[*][2] And 250 have come to Brazil thus far through the special visiting scientist program The national and international companies that joined the program are already competing to offer jobs to the Brazilian students as they return As a result, Brazilian universities are increasingly engaging in international collaborations, with an unprecedented exposure already reflected in international university rankings In the next few years, approximately 3000 Chilean students are expected to return to Chile with doctoral degrees The challenge will be to allocate funding to support their continued training ![Figure][1] Latin American countries are also increasing the number of fellowships to attract talented students from developing countries, including those in Africa and Asia For Brazil, this is being done in association with the Brazilian foreign ministry and international organizations such as The World Academy of Sciences (TWAS) and the United Nations Educational, Scientific and Cultural Organization (UNESCO) Within Latin America, the South American Support Program of Science and Technology (PROSUL) is supporting all South American countries, with funding for joint research projects and for scientific events and research networking Other successful programs include the Iberoamerican Program of Science and Technology (CYTED) and the African Thematic Program of Cooperation in Science and Technology (PROAFRICA) Latin America must continue to strengthen the internationalization of its science, as well as exploit its local excellence through intracontinental collaborations, positioning the continent to become a global leader in science, technology, and innovation Indeed, every nation can benefit by growing a capable and knowledgeable workforce [1]: pending:yes [2]: #fn-1

Melanoma vaccines and modulation of the immune system in the clinical setting: building from new realities.

Abstract: To endow the immune system with the capacity to fight cancer has always attracted attention, although the clinical results obtained have been until recently disappointing. Cutaneous melanoma is a highly immunogenic tumor; therefore most of the attempts to produce cancer vaccines have been addressed to this disease. New advances in the comprehension of the mechanisms of antigen presentation by dendritic cells, in the immune responses triggered by adjuvants, as well as the understanding of the role of immunosuppressor molecules such as cytotoxic T-lymphocyte antigen-4 (CTLA-4), which led to the recent approval of the anti-CTLA-4 monoclonal antibody ipilimumab, have opened new hopes about the installment of immunotherapy as a new modality to treat cancer.

Autophagic paintings: In the frontier of art and science

Abstract: As a PhD student I explored macroautophagy/autophagy induced by starvation in Drosophila melanogaster using different microscopy techniques. The beauty and complexity of this process impressed me so deeply that I felt the need to paint it. Thus, I made 2 oil paintings based on my own scientific work, representing the autophagy mechanism at different scales with diverse artistic resources. The first painting, called Autophagy 1, is inspired by fluorescence confocal microscopy images. Therefore, saturated colors predominate in the composition. The second one is an oil on canvas titled Autophagy 2 which reflects autophagy at a smaller scale. This painting depicts this process as revealed by transmission electron microscopy, employing mainly a gray scale of colors. I performed these works with the intention to catch the essence of this biological process, conveying scientific ideas through art. My paintings are not intended only for the scientific community but also for the general public, as an instrument of enjoyment and popularization of science.