University of Aberdeen

About: University of Aberdeen is a education organization based out in Aberdeen, United Kingdom. It is known for research contribution in the topics: Population & Health care. The organization has 21174 authors who have published 49962 publications receiving 2105479 citations. The organization is also known as: Aberdeen University.

Role of the Hog1 Stress-activated Protein Kinase in the Global Transcriptional Response to Stress in the Fungal Pathogen Candida albicans

Abstract: The resistance of Candida albicans to many stresses is dependent on the stress-activated protein kinase (SAPK) Hog1. Hence we have explored the role of Hog1 in the regulation of transcriptional res...

Teleost fish interferons and their role in immunity.

Abstract: Interferons (IFNs) are the hallmark of the vertebrate antiviral system. Two of the three IFN families identified in higher vertebrates are now known to be important for antiviral defence in teleost fish. Based on the cysteine patterns, the fish type I IFN family can be divided into two subfamilies, which possibly interact with distinct receptors for signalling. The fish type II IFN family consists of two members, IFN-γ with similar functions to mammalian IFN-γ and a teleost specific IFN-γ related (IFN-γrel) molecule whose functions are not fully elucidated. These two type II IFNs also appear to bind to distinct receptors to exert their functions. It has become clear that fish IFN responses are mediated by the host pattern recognition receptors and an array of transcription factors including the IFN regulatory factors, the Jak/Stat proteins and the suppressor of cytokine signalling (SOCS) molecules.

Footprints through the weather-world: walking, breathing, knowing

Abstract: Le present essai etudie la relation entre l'acquisition de connaissances, la deambulation et la perception du temps qu'il fait. Pour commencer, il explore la signification du sol. Loin d'etre uniforme, homogene et prepare, le sol est divers, composite et en recreation constante. Il est en outre apprehende en mouvement plutot qu'a partir de points fixes. En marchant sur le sol, les gens creent des pistes et des chemins. Ceux-ci sont produits par des traces de pas plutot que par un geste d'inscription. Des lors que ces empreintes s'inscrivent dans un sol meuble au lieu d'etre imprimees sur une surface dure, leur temporalite est liee a la dynamique de leur formation, qui depend elle-meme du temps qu'il fait et des reactions a l'interface entre la terre et l'air. En respirant a chaque pas, les marcheurs deambulent a la fois dans l'air et sur terre. Marcher est donc en soi un processus de reflexion et de connaissance. C'est ainsi que le savoir nait le long des chemins de deplacement traversant le monde des elements.