University of Houston

About: University of Houston is a education organization based out in Houston, Texas, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 23074 authors who have published 53903 publications receiving 1641968 citations.

The different roles of ER subtypes in cancer biology and therapy

Abstract: By eliciting distinct transcriptional responses, the oestrogen receptors (ERs) ERα and ERβ exert opposite effects on cellular processes that include proliferation, apoptosis and migration and that differentially influence the development and the progression of cancer. Perturbation of ER subtype-specific expression has been detected in various types of cancer, and the differences in the expression of ERs are correlated with the clinical outcome. The changes in the bioavailability of ERs in tumours, together with their specific biological functions, promote the selective restoration of their activity as one of the major therapeutic approaches for hormone-dependent cancers.

Evidence on the Joint Determination of Audit and Non‐Audit Fees

Abstract: In this study we investigate whether the characteristics of clients, auditors, and the auditor-client relationship simultaneously determine audit and non-audit fees. As done in prior studies, we maintain that fees proxy for the level of service provided and follow the physical flow of knowledge. Estimating single-equation models of audit and non-audit fee models, we confirm prior findings of an association between audit and non-audit fees. Studies conclude that such evidence is consistent with knowledge spillovers between the two services. However, we document empirically that audit and non-audit fees are simultaneously determined. Because the data indicate audit and non-audit fees are jointly determined, we then investigate whether previously documented associations between audit and non-audit fees are the result of biased estimation induced by using endogenous variables in single-equation models. In contrast to results from single-equation estimations, we find no association between audit and non-audit fees using a simultaneous specification of the fee system, suggesting that single-equation estimations suffer from simultaneous-equations bias. In sum, the findings are not consistent with the existence of economies of scope from the joint performance of audit and non-audit services after controlling for the joint behavior of audit and non-audit fees. Given the ongoing debate over the level of allowed non-audit services by auditors, the argument for the joint provision of audit and non-audit services is less justified than if joint-supply benefits had been documented.

The future of plastics recycling

Abstract: The environmental consequences of plastic solid waste are visible in the ever-increasing levels of global plastic pollution both on land and in the oceans. But although there are important economic and environmental incentives for plastics recycling, end-of-life treatment options for plastic solid waste are in practice quite limited. Presorting of plastics before recycling is costly and time-intensive, recycling requires large amounts of energy and often leads to low-quality polymers, and current technologies cannot be applied to many polymeric materials. Recent research points the way toward chemical recycling methods with lower energy requirements, compatibilization of mixed plastic wastes to avoid the need for sorting, and expanding recycling technologies to traditionally nonrecyclable polymers.

The employment interview: A summary and review of recent research.

Abstract: After a quick recapitulation of previous reviews of the employment interview, recent research from about 1975 is reviewed and summarized. Research dealing with the reliability and validity of the interview, methodological issues, decision making, interviewer training, minority characteristics, nonverbal behavior, interviewee characteristics, and interviewee training is summarized. Trends and directions are noted, suggestions for further research extended, and a discussion of why persistence in the use of interview exists is presented.

Current status and future directions of multivalent metal-ion batteries

Abstract: Batteries based on multivalent metals have the potential to meet the future needs of large-scale energy storage, due to the relatively high abundance of elements such as magnesium, calcium, aluminium and zinc in the Earth’s crust. However, the complexity of multivalent metal-ion chemistries has led to rampant confusions, technical challenges, and eventually doubts and uncertainties about the future of these technologies. In this Review, we clarify the key strengths as well as common misconceptions of multivalent metal-based batteries. We then examine the growth behaviour of metal anodes, which is crucial for their safety promises but hitherto unestablished. We further discuss scrutiny of anode efficiency and cathode storage mechanism pertaining to complications arising from electrolyte solutions. Finally, we critically review existing cathode materials and discuss design strategies to enable genuine multivalent metal-ion-based energy storage materials with competitive performance. Batteries based on multivalent metal anodes hold great promise for large-scale energy storage but their development is still at an early stage. This Review surveys the main complexity arising from anodes, electrolytes and cathodes, and offers views on the progression path of these technologies.