Institution
University of Houston
Education•Houston, Texas, United States•
About: University of Houston is a education organization based out in Houston, Texas, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 23074 authors who have published 53903 publications receiving 1641968 citations.
Topics: Population, Poison control, Anxiety, Context (language use), Catalysis
Papers published on a yearly basis
Papers
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University of Washington1, Pacific Northwest National Laboratory2, University of Wisconsin-Madison3, Radcliffe Institute for Advanced Study4, Eindhoven University of Technology5, University of Minnesota6, Lawrence Berkeley National Laboratory7, Northwestern University8, University of California, Berkeley9, University of Houston10, University of California, Davis11, University of Delaware12, Virginia Tech13, University of Leeds14, University of Konstanz15
TL;DR: The current understanding of CPA is described, some of the nonclassical thermodynamic and dynamic mechanisms known to give rise to experimentally observed pathways are examined, and the challenges to the understanding of these mechanisms are highlighted.
Abstract: Field and laboratory observations show that crystals commonly form by the addition and attachment of particles that range from multi-ion complexes to fully formed nanoparticles. The particles involved in these nonclassical pathways to crystallization are diverse, in contrast to classical models that consider only the addition of monomeric chemical species. We review progress toward understanding crystal growth by particle-attachment processes and show that multiple pathways result from the interplay of free-energy landscapes and reaction dynamics. Much remains unknown about the fundamental aspects, particularly the relationships between solution structure, interfacial forces, and particle motion. Developing a predictive description that connects molecular details to ensemble behavior will require revisiting long-standing interpretations of crystal formation in synthetic systems, biominerals, and patterns of mineralization in natural environments.
1,357 citations
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TL;DR: All tissues and organs were reconstructed as three-dimensional unstructured triangulated surface objects, yielding high precision images of individual features of the body, which greatly enhances the meshing flexibility and the accuracy in comparison with the traditional voxel-based representation of anatomical models.
Abstract: The objective of this study was to develop anatomically correct whole body human models of an adult male (34 years old), an adult female (26 years old) and two children (an 11-year-old girl and a six-year-old boy) for the optimized evaluation of electromagnetic exposure. These four models are referred to as the Virtual Family. They are based on high resolution magnetic resonance (MR) images of healthy volunteers. More than 80 different tissue types were distinguished during the segmentation. To improve the accuracy and the effectiveness of the segmentation, a novel semi-automated tool was used to analyze and segment the data. All tissues and organs were reconstructed as three-dimensional (3D) unstructured triangulated surface objects, yielding high precision images of individual features of the body. This greatly enhances the meshing flexibility and the accuracy with respect to thin tissue layers and small organs in comparison with the traditional voxel-based representation of anatomical models. Conformal computational techniques were also applied. The techniques and tools developed in this study can be used to more effectively develop future models and further improve the accuracy of the models for various applications. For research purposes, the four models are provided for free to the scientific community.
1,347 citations
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TL;DR: Although 16S rRNA sequences can be used routinely to distinguish and establish relationships between genera and well-resolved species, very recently diverged species may not be recognizable.
Abstract: 16S rRNA (genes coding for rRNA) sequence comparisons were conducted with the following three psychrophilic strains: Bacillus globisporus W25T (T = type strain) and Bacillus psychrophilus W16AT, and W5. These strains exhibited more than 99.5% sequence identity and within experimental uncertainty could be regarded as identical. Their close taxonomic relationship was further documented by phenotypic similarities. In contrast, previously published DNA-DNA hybridization results have convincingly established that these strains do not belong to the same species if current standards are used. These results emphasize the important point that effective identity of 16S rRNA sequences is not necessarily a sufficient criterion to guarantee species identity. Thus, although 16S rRNA sequences can be used routinely to distinguish and establish relationships between genera and well-resolved species, very recently diverged species may not be recognizable.
1,342 citations
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TL;DR: Comparisons of circadian clocks in unicellular and multicellular organisms using molecular genetics and genomics have provided new insights into the mechanisms and complexity of clock systems.
Abstract: The organization of biological activities into daily cycles is universal in organisms as diverse as cyanobacteria, fungi, algae, plants, flies, birds and man. Comparisons of circadian clocks in unicellular and multicellular organisms using molecular genetics and genomics have provided new insights into the mechanisms and complexity of clock systems. Whereas unicellular organisms require stand-alone clocks that can generate 24-hour rhythms for diverse processes, organisms with differentiated tissues can partition clock function to generate and coordinate different rhythms. In both cases, the temporal coordination of a multi-oscillator system is essential for producing robust circadian rhythms of gene expression and biological activity.
1,316 citations
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01 Mar 2012TL;DR: This latest edition offers an unparalleled presentation of drug discovery and pharmacodynamic agents, integrating principles of medicinal chemistry with pharmacology, pharmacokinetics, and clinical pharmacy.
Abstract: Acclaimed by students and instructors alike, "Foye's Principles of Medicinal Chemistry "is now in its Seventh Edition, featuring updated chapters plus new material that meets the needs of today's medicinal chemistry courses. This latest edition offers an unparalleled presentation of drug discovery and pharmacodynamic agents, integrating principles of medicinal chemistry with pharmacology, pharmacokinetics, and clinical pharmacy. All the chapters have been written by an international team of respected researchers and academicians. Careful editing ensures thoroughness, a consistent style and format, and easy navigation throughout the text.
1,314 citations
Authors
Showing all 23345 results
Name | H-index | Papers | Citations |
---|---|---|---|
Matthew Meyerson | 194 | 553 | 243726 |
Gad Getz | 189 | 520 | 247560 |
Eric Boerwinkle | 183 | 1321 | 170971 |
Pulickel M. Ajayan | 176 | 1223 | 136241 |
Zhenan Bao | 169 | 865 | 106571 |
Marc Weber | 167 | 2716 | 153502 |
Steven N. Blair | 165 | 879 | 132929 |
Martin Karplus | 163 | 831 | 138492 |
Dongyuan Zhao | 160 | 872 | 106451 |
Xiang Zhang | 154 | 1733 | 117576 |
Jan-Åke Gustafsson | 147 | 1058 | 98804 |
James M. Tour | 143 | 859 | 91364 |
Guanrong Chen | 141 | 1652 | 92218 |
Naomi J. Halas | 140 | 435 | 82040 |
Antonios G. Mikos | 138 | 694 | 70204 |