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Institution

University of New South Wales

EducationSydney, New South Wales, Australia
About: University of New South Wales is a education organization based out in Sydney, New South Wales, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 51197 authors who have published 153634 publications receiving 4880608 citations. The organization is also known as: UNSW & UNSW Australia.


Papers
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Journal ArticleDOI
TL;DR: Green et al. as discussed by the authors presented consolidated tables showing an extensive listing of the highest independently confirmed efficiencies for solar cells and modules, and guidelines for inclusion of results into these tables are outlined and new entries since June 2016 are reviewed.
Abstract: Consolidated tables showing an extensive listing of the highest independently confirmed efficiencies for solar cells and modules are presented. Guidelines for inclusion of results into these tables are outlined and new entries since June 2016 are reviewed. URI: http://onlinelibrary.wiley.com/doi/10.1002/pip.2855/abstract [1] Authors: GREEN Martin A. EMERY Keith HISHIKAWA Y. WARTA W. DUNLOP Ewan LEVI Dean HO-BAILLIE Anita Publication Year: 2017 Science Areas: Energy and transport [2]

626 citations

Journal ArticleDOI
18 Feb 2000-AIDS
TL;DR: The NRTI-LD syndrome differed from protease inhibitor-related LD syndrome by the presence of recent onset symptoms and weight loss, higher lactate and alanine aminotransferase, and lower albumin, cholesterol, triglycerides, glucose and insulin.
Abstract: Background: Lipodystrophy (LD; peripheral lipoatrophy, central adiposity) hyperlipidaemia and insulin resistance often complicate protease inhibitor-containing antiretroviral therapy. Lipoatrophy and abdominal distension were observed in protease inhibitor-naive nucleoside analogue reverse transcriptase inhibitor (NRTI) recipients with lactic acidaemia and hepatic impairment, which are known NRTI-induced mitochondrial toxicities. Design and setting: Case-control study in a university-based outpatient clinic. Patients and methods: The patients studied included 14 NRTI recipients with lipoatrophy, 32 antiretroviral-naive patients without LD, 28 NRTI recipients without LD, 44 combined NRTI-protease inhibitor recipients without LD, and 102 NRTI-protease inhibitor recipients with LD. Data was obtained on body composition (questionnaire, physical examination, dual-energy x-ray absorptiometry and abdominal computerized tomography), with biochemical, lipid and glycaemic parameters. Results: The NRTI-LD syndrome was characterized by recent onset fatigue and nausea, peripheral lipoatrophy (6 kg loss over 4 months), abdominal distension (ascites ± hepatomegaly) and elevated lactate (4.6, 1.1, 1.2, 1.4 and 1.7 mmol/l, respectively; P< 0.0001) and liver enzymes. Cases without hepatic involvement also had lower body fat and greater lactate than unaffected controls. Metabolic disturbances and weight improved after cessation. The NRTI-LD syndrome differed from protease inhibitor-related LD syndrome by the presence of recent onset symptoms and weight loss, higher lactate and alanine aminotransferase, and lower albumin, cholesterol, triglycerides, glucose and insulin. In treated controls, current stavudine therapy, protease inhibitor duration, and lactic acidaemia were independently associated with both lipoatrophy and abdominal obesity; total NRTI duration was also associated with lipoatrophy, and lamivudine and protease inhibitor duration with buffalo hump. Conclusions: A syndrome of lipoatrophy, constitutional illness, lactic acidaemia and hepatic dysfunction can complicate NRTI therapy. Both protease inhibitor and NRTI therapies, particularly if associated with lactic acidaemia, contribute to LD syndrome, but have some distinguishable clinical and metabolic effects.

624 citations

Journal ArticleDOI
TL;DR: In this article, the role of boundary objects in an organization's accounting system can be illustrated by a heterogeneous actor-network of local and global actors and actants, focusing on the roles of boundary that were able to stabilise and mediate diverse interests.
Abstract: This field study seeks to illustrate how an organisation's accounting system can be changed by a heterogeneous actor-network of local and global actors and actants. In particular, it focusses on the role of boundary that were able to stabilise and mediate diverse interests. Five types of boundary objects were identified — data repositories, visionary objects ideal type objects, coincident boundaries and standardized protocols. Here, accounting change was anti-heroic — the effort of many as opposed to a powerful few had to be corralled. Also, change was cyclical, as new accounting technologies were adopted on faith, made to ‘work/succeed’ temporarily, and then abandoned.

624 citations

Journal ArticleDOI
02 Jan 2014-Nature
TL;DR: The mixing inferred from observations appears to be sufficiently strong to imply a climate sensitivity of more than 3 degrees for a doubling of carbon dioxide, significantly higher than the currently accepted lower bound of 1.5 degrees, thereby constraining model projections towards relatively severe future warming.
Abstract: Equilibrium climate sensitivity refers to the ultimate change in global mean temperature in response to a change in external forcing. Despite decades of research attempting to narrow uncertainties, equilibrium climate sensitivity estimates from climate models still span roughly 1.5 to 5 degrees Celsius for a doubling of atmospheric carbon dioxide concentration, precluding accurate projections of future climate. The spread arises largely from differences in the feedback from low clouds, for reasons not yet understood. Here we show that differences in the simulated strength of convective mixing between the lower and middle tropical troposphere explain about half of the variance in climate sensitivity estimated by 43 climate models. The apparent mechanism is that such mixing dehydrates the low-cloud layer at a rate that increases as the climate warms, and this rate of increase depends on the initial mixing strength, linking the mixing to cloud feedback. The mixing inferred from observations appears to be sufficiently strong to imply a climate sensitivity of more than 3 degrees for a doubling of carbon dioxide. This is significantly higher than the currently accepted lower bound of 1.5 degrees, thereby constraining model projections towards relatively severe future warming.

623 citations

Journal ArticleDOI
TL;DR: A review of the latest advances of bio-functionalized carbon nanotubes with an emphasis on the development of functional biological nano-interfaces can be found in this paper, where the authors discuss methods for biomodification of carbon-nanotubes, the developed of hybrid systems of carbon and biomolecules for bioelectronics, and carbon-notubes as transporters for a specific delivery of peptides and/or genetic material to cells.
Abstract: Ever since the discovery of carbon nanotubes, researchers have been exploring their potential in biological and biomedical applications. The recent expansion and availability of chemical modification and bio-functionalization methods have made it possible to generate a new class of bioactive carbon nanotubes which are conjugated with proteins, carbohydrates, or nucleic acids. The modification of a carbon nanotube on a molecular level using biological molecules is essentially an example of the 'bottom-up' fabrication principle of bionanotechnology. The availability of these biomodified carbon nanotube constructs opens up an entire new and exciting research direction in the field of chemical biology, finally aiming to target and to alter the cell's behaviour at the subcellular or molecular level. This review covers the latest advances of bio-functionalized carbon nanotubes with an emphasis on the development of functional biological nano-interfaces. Topics that are discussed herewith include methods for biomodification of carbon nanotubes, the development of hybrid systems of carbon nanotubes and biomolecules for bioelectronics, and carbon nanotubes as transporters for a specific delivery of peptides and/or genetic material to cells. All of these current research topics aim at translating these biotechnology modified nanotubes into potential novel therapeutic approaches.

623 citations


Authors

Showing all 51897 results

NameH-indexPapersCitations
Ronald C. Kessler2741332328983
Nicholas G. Martin1921770161952
John C. Morris1831441168413
Richard S. Ellis169882136011
Ian J. Deary1661795114161
Nicholas J. Talley158157190197
Wolfgang Wagner1562342123391
Bruce D. Walker15577986020
Xiang Zhang1541733117576
Ian Smail15189583777
Rui Zhang1512625107917
Marvin Johnson1491827119520
John R. Hodges14981282709
Amartya Sen149689141907
J. Fraser Stoddart147123996083
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023389
20221,183
202111,342
202011,235
20199,891
20189,145