Institution
University of Zambia
Education•Lusaka, Lusaka, Zambia•
About: University of Zambia is a education organization based out in Lusaka, Lusaka, Zambia. It is known for research contribution in the topics: Population & Health care. The organization has 2593 authors who have published 4402 publications receiving 122411 citations. The organization is also known as: UNZA.
Papers published on a yearly basis
Papers
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University of Pretoria1, University of Botswana2, University of Adelaide3, University of Bamenda4, University of Ghana5, University of Nairobi6, University of Namibia7, Ekiti State University8, Lagos State University9, Sefako Makgatho Health Sciences University10, University of the Witwatersrand11, Qassim University12, Memorial Hospital of South Bend13, University of Zambia14, College of Health Sciences, Bahrain15, University of Liverpool16, Strathclyde Institute of Pharmacy and Biomedical Sciences17, Hawler Medical University18, NHS Lothian19, RMIT University20, University of Manchester21
TL;DR: There are a number of ongoing activities across Africa to improve the management of patients with diabetes including co-morbidities, however, more needs to be done considering the high and growing burden of T2DM in Africa.
Abstract: Background: There has been an appreciable increase in the number of people in Africa with metabolic syndrome and Type 2 diabetes (T2DM) in recent years as a result of a number of factors. Factors include lifestyle changes, urbanisation, and the growing consumption of processed foods coupled with increasing levels of obesity. Currently there are 19 million adults in Africa with diabetes, mainly T2DM (95%), estimated to grow to 47 million people by 2045 unless controlled. This has a considerable impact on morbidity, mortality and costs in the region. There are a number of issues to address to reduce the impact of T2DM including improving detection rates and current access to services alongside addressing issues of adherence to prescribed medicines. There are also high rates of co-morbidities with infectious diseases such as HIV and tuberculosis in patients in Africa with T2DM that require attention. Objective: Document ongoing activities across Africa to improve the care of patients with T2DM especially around issues of identification, access, and adherence to changing lifestyles and prescribed medicines. In addition, discussing potential ways forward to improve the care of patients with T2DM based on ongoing activities and experiences including addressing key issues associated with co-morbidities with infectious diseases. Our Approach: Contextualise the findings from a wide range of publications including internet based publications of national approaches coupled with input from senior level government, academic and other professionals from across Africa to provide future guidance. Ongoing Activities: A number of African countries are actively instigating programmes to improve the care of patients with T2DM starting with improved diagnosis. This recognises the growing burden of non-communicable diseases across Africa, which has been neglected in the past. Planned activities include programmes to improve detection rates and address key issues with diet and lifestyle changes, alongside improving monitoring of care and activities to enhance adherence to prescribed medicines. In addition, addressing potential complexities involving diabetes patients with infectious disease co-morbidities. It is too early to fully assess the impact of such activities, Conclusion: There are a number of ongoing activities across Africa to improve the management of patients with diabetes including co-morbidities. However, more needs to be done considering the high and growing burden of T2DM in Africa. Ongoing research will help further benefit resource allocation and subsequent care.
80 citations
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Aniruddha Deshpande1, Molly K. Miller-Petrie2, Paulina A. Lindstedt2, Mathew M. Baumann2 +702 more•Institutions (292)
TL;DR: High-resolution geospatial estimates of access to drinking water and sanitation facilities in low-income and middle-income countries from 2000 to 2017 identify areas with successful approaches or in need of targeted interventions to enable precision public health to effectively progress towards universal access to safe water and sanitary facilities.
80 citations
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TL;DR: To estimate and compare the performances of coprology, copro‐Ag ELISA and real‐time polymerase chain reaction assay (copro‐PCR) for detection of Taenia solium tapeworm carriers.
Abstract: objective To estimate and compare the performances of coprology, copro-Ag ELISA and real-time polymerase chain reaction assay (copro-PCR) for detection of Taenia solium tapeworm carriers. methods The three diagnostic tests were applied on 817 stool samples collected in two Zambian communities where taeniasis is endemic. A Bayesian approach was used to allow estimation of the test characteristics. Two (0.2%; 95% Confidence Interval (CI): 0–0.8), 67 (8.2%; 95% CI: 6.4–10.3) and 10 (1.2%; 95% CI: 0.5–2.2) samples were positive using coprology, copro-Ag ELISA and coproPCR, respectively. results Specificities of 99.9%, 92.0% and 99.0% were determined for coprology, copro-Ag ELISA and copro-PCR, respectively. Sensitivities of 52.5%, 84.5% and 82.7% were determined for coprology, copro-Ag ELISA and copro-PCR, respectively. conclusions We urge for additional studies exploring possible cross-reactions of the copro-Ag ELISA and for the use of more sensitive tests, such as copro-PCR, for the detection of tapeworm carriers, which is a key factor in controlling the parasite in endemic areas.
80 citations
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TL;DR: In this paper, the authors presented a projected climate over the Greater Horn of Africa under 1.5 degrees C and 2 degrees C global warming, respectively, under the assumption of a 2.5 degree C and 3 degree C scenario.
Abstract: Projected climate over the Greater Horn of Africa under 1.5 degrees C and 2 degrees C global warming
80 citations
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TL;DR: The implementation of stamping out policy, bleeding and testing animals before movement and promoting the use self-contained units are likely to significantly reduce the public health risks associated with Brucella infections in cattle.
Abstract: A cross-sectional study was conducted to investigate seroprevalence of brucellosis and the associated risk factors in cattle from smallholder dairy farms in Gokwe, Marirangwe, Mushagashe, Nharira, Rusitu and Wedza areas of Zimbabwe. A total of 1,440 cattle from 203 herds were tested serially for Brucella antibodies using Rose Bengal test and the competitive ELISA. Weighted seroprevalence estimates were calculated and risk factors in individual cattle investigated using logistic regression analysis. The overall individual animal brucellosis seroprevalence was low, with mean of 5.6% (95% confidence interval (CI), 4.4%, 6.8%). Gokwe had the highest individual (12.6%; 95% CI, 3.9%, 21.4%) and herd-level (40.0%; 95% CI, 22.1%, 58.0%), while Wedza had the lowest individual (2.3%; 95% CI, 0%, 5.3%) and herd-level (8.0%; 95% CI, 0.0%, 18.9%) brucellosis seroprevalence, respectively. In individual cattle, the area of origin, age and history of abortion were independently associated with brucellosis seroprevalence. While the seroprevalence was independent of sex, it decreased with increasing age. Cattle 2–4 years old had higher odds (odds ratio (OR) = 3.2; 95% CI, 1.1%, 9.1%) of being seropositive compared to those >7 years. Cows with a history of abortion were more likely to be seropositive (OR = 7.9; 95% CI, 3.1, 20.1) than controls. In conclusion, the area-to-area variation of brucellosis may be linked to ecological factors and differences in management practices. The implementation of stamping out policy, bleeding and testing animals before movement and promoting the use self-contained units are likely to significantly reduce the public health risks associated with Brucella infections in cattle.
80 citations
Authors
Showing all 2635 results
Name | H-index | Papers | Citations |
---|---|---|---|
Alimuddin Zumla | 100 | 747 | 43284 |
David Clark | 73 | 652 | 24857 |
Sten H. Vermund | 69 | 606 | 22181 |
Paul A. Kelly | 68 | 208 | 16836 |
Francis Drobniewski | 67 | 293 | 17371 |
Ayato Takada | 67 | 273 | 14467 |
Karl Peltzer | 60 | 880 | 18515 |
Hirofumi Sawa | 55 | 325 | 11735 |
Peter Godfrey-Faussett | 52 | 173 | 8486 |
Igor J. Koralnik | 52 | 197 | 10186 |
Peter Mwaba | 48 | 132 | 7386 |
Alison M. Elliott | 48 | 299 | 7772 |
Kelly Chibale | 47 | 337 | 7713 |
Chihiro Sugimoto | 47 | 325 | 7737 |
Sian Floyd | 47 | 163 | 6791 |