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Biodegradable polymeric nanoparticles as drug delivery devices

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TLDR
This review presents the most outstanding contributions in the field of biodegradable polymeric nanoparticles used as drug delivery systems from 1990 through mid-2000.
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This article is published in Journal of Controlled Release.The article was published on 2001-01-29. It has received 3284 citations till now. The article focuses on the topics: Drug carrier & Drug delivery.

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Citations
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Clicking Pentafluorostyrene Copolymers: Synthesis, Nanoprecipitation, and Glycosylation

TL;DR: Glycopolymers consisting of styrene (St) and pentafluorostyrene (PFS) were synthesized by a combination of nitroxide-mediated polymerization and click chemistry as mentioned in this paper.
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Nanomedicine and drug delivery: a mini review

TL;DR: The field of nanotechnology now has pivotal roles in electronics, biology and medicine and its application can be appraised, as it involves the materials to be designed at atomic and molecular level.
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Nano-magnetic particles used in biomedicine: core and coating materials.

TL;DR: A brief summary on the different ferrite nano-magnetic particles and coatings used in nanomedicine is given.
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Preparation of poly ɛ-caprolactone nanoparticles containing magnetite for magnetic drug carrier

TL;DR: In this paper, magnetic poly epsilon-caprolactone (PCL) nanoparticles were prepared in a well shaped spherical form by the o/w emulsion method.
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A Versatile and Robust Microfluidic Platform Toward High Throughput Synthesis of Homogeneous Nanoparticles with Tunable Properties

TL;DR: A versatile and robust microfluidic nanoprecipitation platform for high throughput synthesis of nanoparticles is fabricated, with homogeneous nanoparticles always being obtained, regardless of the formulation parameters.
References
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Journal ArticleDOI

Biodegradable long-circulating polymeric nanospheres

TL;DR: Monodisperse biodegradable nanospheres were developed from amphiphilic copolymers composed of two biocompatible blocks and exhibited dramatically increased blood circulation times and reduced liver accumulation in mice.
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Polymeric Systems for Controlled Drug Release

TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers

TL;DR: In this paper, a new approach for the preparation of nanoparticles made solely of hydrophilic polymers is presented, based on an ionic gelation process, is extremely mild and involves the mixture of two aqueous phases at room temperature.
Journal ArticleDOI

Protein—surface interactions in the presence of polyethylene oxide

TL;DR: In this paper, the steric repulsion free energy and van der Waals attraction free energy of polyethylene oxide (PEO) chains were calculated as a function of surface density and chain length of PEO.
Book

Principles of tissue engineering

TL;DR: The history and Scope of Tissue Engineering, J.P. Vavanti and C.A. Vacanti, and Quantitative Aspects of Tissues Engineering: Basic Issues in Kinetics, Transport, and Mechanics are reviewed.
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