Journal ArticleDOI
Biodegradable polymeric nanoparticles as drug delivery devices
Reads0
Chats0
TLDR
This review presents the most outstanding contributions in the field of biodegradable polymeric nanoparticles used as drug delivery systems from 1990 through mid-2000.About:
This article is published in Journal of Controlled Release.The article was published on 2001-01-29. It has received 3284 citations till now. The article focuses on the topics: Drug carrier & Drug delivery.read more
Citations
More filters
Journal ArticleDOI
PLA-PEG nanocapsules radiolabeled with 99mTechnetium-HMPAO: release properties and physicochemical characterization by atomic force microscopy and photon correlation spectroscopy.
Maira Alves Pereira,Vanessa Carla Furtado Mosqueira,José Mário Carneiro Vilela,Margareth Spangler Andrade,Gilson Andrade Ramaldes,Valbert Nascimento Cardoso +5 more
TL;DR: The results suggest that the surface-modified 99m Tc-HMPAO-PLA-PEG NC was more stable against label leakage in the presence of proteins and could present better performance as radiotracer in vivo.
Journal ArticleDOI
Formulation and characterization of fast dissolving oral films containing buspirone hydrochloride nanoparticles using design of experiment
TL;DR: In this paper, fast dissolving oral films (FDOFs) containing nanoparticles of buspirone hydrochloride (BH) were prepared by nanoprecipitation method and films were prepared using a solvent casting method.
Journal ArticleDOI
Polymeric Nanomedicines Based on Poly(lactide) and Poly(lactide-co-glycolide).
TL;DR: The development and use of PLA and PLGA for the delivery of chemotherapeutic agents in the forms of polymer-drug conjugates and nanoconjugates are reviewed.
Journal ArticleDOI
Methacrylic-based nanogels for the pH-sensitive delivery of 5-fluorouracil in the colon.
TL;DR: Western blot analysis and flow cytometry studies confirmed that the nanogels could be successfully used as an efficient vector for pH-sensitive and controlled delivery of drugs specifically targeted to the colon.
Journal ArticleDOI
When Sustainable Nanochemistry Meets Agriculture: Lignin Nanocapsules for Bioactive Compound Delivery to Plantlets
Sara Falsini,Ilaria Clemente,Ilaria Clemente,Alessio Papini,Corrado Tani,Silvia Schiff,Maria Cristina Salvatici,Raffaella Petruccelli,Carla Benelli,Cristiana Giordano,Cristina Gonnelli,Sandra Ristori +11 more
TL;DR: First developed for biomedical and industrial applications, nanovectors have recently been extended to agriculture and innovative plant-growing procedures making use of nanoparticles should be made use of.
References
More filters
Journal ArticleDOI
Biodegradable long-circulating polymeric nanospheres
Ruxandra Gref,Yoshiharu Minamitake,Maria Teresa Peracchia,Vladimir S. Trubetskoy,Vladimir P. Torchilin,Robert Langer +5 more
TL;DR: Monodisperse biodegradable nanospheres were developed from amphiphilic copolymers composed of two biocompatible blocks and exhibited dramatically increased blood circulation times and reduced liver accumulation in mice.
Journal ArticleDOI
Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI
Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers
TL;DR: In this paper, a new approach for the preparation of nanoparticles made solely of hydrophilic polymers is presented, based on an ionic gelation process, is extremely mild and involves the mixture of two aqueous phases at room temperature.
Journal ArticleDOI
Protein—surface interactions in the presence of polyethylene oxide
TL;DR: In this paper, the steric repulsion free energy and van der Waals attraction free energy of polyethylene oxide (PEO) chains were calculated as a function of surface density and chain length of PEO.
Book
Principles of tissue engineering
TL;DR: The history and Scope of Tissue Engineering, J.P. Vavanti and C.A. Vacanti, and Quantitative Aspects of Tissues Engineering: Basic Issues in Kinetics, Transport, and Mechanics are reviewed.
Related Papers (5)
Biodegradable nanoparticles for drug and gene delivery to cells and tissue
Jayanth Panyam,Vinod Labhasetwar +1 more